Prenatal ethanol exposure results in increased glucose production in adult rat offspring and this may involve modulation of protein acetylation by cellular stress. We used adult male offspring of dams given ethanol during gestation days 1-7 (early), 8-14 (mid) and 15-21 (late) compared with those from control dams. A group of ethanol offspring was treated with tauroursodeoxycholic acid (TUDCA) ...

Nutrient and oxygen (O2) deprivation are frequent in solid cancers. Angiogenesis is activated early in cancer growth, however, the newly formed vascular network is aberrant and shows irregular blood flow [1]. Moreover, cancer cells themselves contribute to gradients for nutrients like glucose due to high consumption. The concentration of glucose was estimated to be on average 3 to 10 times lowe...

The objective of the present study was to investigate the polymorphism of prolactin promoter and cytosolicphosphoenol pyruvate carboxykinase (PEPCK-C) intron 3 to exon 3 regions, and its association with economictraits in native fowl of Yazd province. These traits consisted of body weight at 8 (BW8) and 12 (BW12) weeks of age, age at sexual maturity (ASM), weight at sexual maturity ...

Hepatic dysfunction is commonly observed in subjects with hyperthyroidism. Hepassocin a hepatokine playing an important role metabolic diseases and exhibiting hepatic protective effect. Nevertheless, the relationship between hepassocin hyperthyroidism was still unknown. In present study, total of 36 Graves’ disease were enrolled, we found that alanine aminotransferase (ALT) levels significantly...

Abstract Tropical xero-epiphytic orchids undergo a photosynthetic mechanism called ‘Crassulacean Acid Metabolism’, modification of Calvin–Benson cycle. This anabolic process aids in the long-term retention organically fixed CO 2 , imprinting them as active sequestrators and fixers gaseous . The malate decarboxylation competence enzymes—phosphoenolpyruvate carboxykinase (PEPCK), Nicotinamide Ade...

Transgenic animals expressing genes capable of repairing DNA may be a valuable tool to study the effect of DNA-damaging agents on tissue-specific carcinogenesis. For this reason, we constructed a chimeric gene consisting of the promoter-regulatory region of the phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) gene linked to the Escherichia coli ada gene coding for O6-alkylguanine-D...

TWO ROUTES FOR SYNTHESIS OF PHOSP~OENOLP~~ATE FROM C4-DICARBOXYLIC AICDS IN ESCHKRICHIA COLI Eric J. Hansen and Elliot Juni Department of Microbiology The University of Michigan Ann Arbor, Michigan 48104 Received June 28,1974 SUMMARY Mutants of s. coli defective in both phosphoenolpyruvate carboxykinase and phosphoenolpyruvate synthetase are unable to use C4-dicarboxylic acids such as suecinate...

The activities of pyruvate carboxylase (PC), phosphoenolpyruvate carboxykinase (PEPCK), glucose-6-phosphatase (G6Pase), and glycogen synthetase (GS) were determined in the cancerous and in the apparently uninvolved (host) regions of livers from primary hepatoma patients as well as in normal adult human livers and human fetal livers. The activities of these enzymes were also assayed in a fairly ...

The activities of pyruvate carboxylase (PC), phosphoenolpyruvate carboxykinase (PEPCK), glucose-6-phosphatase (GGPase), and glycogen synthetase (GS) were determined in the cancerous and in the apparently uninvolved (host) regions of livers from primary hepatoma patients as well as in normal adult human livers and human fetal livers. The activities of these enzymes were also assayed in a fairly ...

HYPOTHESIS Palmitate causes insulin resistance (IR) in insulin target tissue. Pioglitazone (an anti-hyperglycemic agent) and epigallocatechin gallate (EGCG, a dietary supplement) can be used for the treatment of type 2 diabetes. However, their molecular effects on gluconeogenesis remain unclear. OBJECTIVE Hence, we aimed to investigate the simultaneous effect of these anti-hyperglycemic agent...