نتایج جستجو برای: ژن ox40l

تعداد نتایج: 16061  

1998
Sarah Flynn Kai-Michael Toellner Chandra Raykundalia Margaret Goodall Peter Lane

This report investigates the role of OX40 ligand (OX40L) and its receptor, OX40, expressed on activated B and T cells, respectively, in promoting the differentiation of T helper type 2 (Th2) CD4 T cells. These molecules are expressed in vivo by day 2 after priming with T cell– dependent antigens. Their expression coincides with the appearance of immunoglobulin (Ig)G switch transcripts and mRNA ...

2014
Alba Llop-Guevara Derek K. Chu Tina D. Walker Susanna Goncharova Ramzi Fattouh Jonathan S. Silver Cheryl Lynn Moore Juliana L. Xie Paul M. O’Byrne Anthony J. Coyle Roland Kolbeck Alison A. Humbles Martin R. Stämpfli Manel Jordana

Allergic asthma is a chronic immune-inflammatory disease of the airways. Despite aeroallergen exposure being universal, allergic asthma affects only a fraction of individuals. This is likely related, at least in part, to the extent of allergen exposure. Regarding house dust mite (HDM), we previously identified the threshold required to elicit allergic responses in BALB/c mice. Here, we investig...

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