The Healthy Life Years (HLY) indicator is the official European Union and a cornerstone of many health policies used in over 15 countries EU region to set national plans monitor targets. It also investigate trends time proportion total life years spent good or poor health, socioeconomic inequalities mortality male-female survival paradox. Based on Global Activity Limitation Indicator (GALI) inc...

Spermatozoa mediated gene transfer has become a promising technology to generate transgenic animals with disease resistance. However, exogenous DNA invasion may cause changes in spermatozoon natural defense system which result in spermatozoon dysfunction.The objective of this study was to investigate the changes of mitochondrial function and motility in goat spermatozoa after pre-incubation and...

Listeria monocytogenes evades the antimicrobial mechanisms of macrophages by escaping from the phagosome into the cytosolic space via a unique cytolysin that targets the phagosomal membrane, listeriolysin O (LLO), encoded by hly. Gamma interferon (IFN-gamma), which is known to play a pivotal role in the induction of Th1-dependent protective immunity in mice, appears to be produced, depending on...

Cholera is an intestinal infection caused by Vibrio cholerae. The hallmark of the disease is profuse secretory diarrhea. Cholera can be endemic, epidemic, or pandemic. A total of 15 Vibrio cholerae isolates were obtained from diarrheal samples by standard bacteriological and serological methods. After DNA extraction, a polymerase chain reaction (PCR) assay was performed for detection of the pre...

Abstract Background Cost effectiveness was a criterion used to revise Ethiopia’s essential health service package (EHSP) in 2019. However, there are few cost-effectiveness studies from Ethiopia or directly transferable evidence other low-income countries inform comprehensive revision of the Ethiopian EHSP. Therefore, this paper reports average ratios (ACERs) 159 interventions Methods In study, ...

Escherichia coli hemolysin, a transmembrane pore-forming exotoxin, is considered an important virulence factor for E. coli-related extraintestinal infections and sepsis. The possible significance of hemolysin liberation for induction of inflammatory lipid mediators was investigated in isolated rabbit lungs infused with viable bacteria (concentration range, 10(4)-10(7)/ml). Hemolysin-secreting E...