Systemic hypoxia, produced by lowering inspired Po2, induces a rapid inflammation in several microcirculations, including cremaster muscle. Mast cell activation is a necessary element of this response. Selective reduction of cremaster microvascular Po2 (PmO2) with normal systemic arterial Po2 (PaO2; cremaster hypoxia/systemic normoxia), however, does not elicit increased leukocyte-endothelial a...

OBJECTIVE The objective of this study was to evaluate the association between foot ulcers (DFU) and lower-extremity amputation (LEA) and chronic kidney disease (CKD) in patients with diabetes. RESARCH DESIGN AND METHODS: This was a retrospective cohort study of individuals enrolled between 2002 and 2006 who were aged > or =35 years, had a history of diabetes, and were cared for in general pract...

Late embryogenesis abundant (LEA) proteins are a large and highly diverse gene family present in a wide range of plant species. LEAs are proposed to play a role in various stress tolerance responses. Our study represents the first-ever survey of LEA proteins and their encoding genes in a widely distributed pine (Pinus tabuliformis) in China. Twenty-three LEA genes were identified from the P. ta...

The GPR119 receptor plays an important role in the secretion of incretin hormones in response to nutrient consumption. We have studied the ability of an array of naturally occurring endocannabinoid-like lipids to activate GPR119 and have identified several lipid receptor agonists. The most potent receptor agonists identified were three N-acylethanolamines: oleoylethanolamine (OEA), palmitoleoyl...

OBJECTIVE There is a lack of continuous longitudinal population-based data on lower extremity amputation (LEA) in the U.K. We present here accurate data on trends in diabetes-related (DR) LEAs and non-DRLEAs in the South Tees area over a continuous 5-year period. RESEARCH DESIGN AND METHODS All cases of LEA from 1 July 1995 to 30 June 2000 within the area were identified. Estimated ascertainm...

The editorial board of Cognitive Science had mixed emotions on hearing the news that Larry Erlbaum was selling Lawrence Erlbaum Associates (LEA) to Informa, parent company of Taylor and Francis. Larry has been an ardent supporter of the Cognitive Science Society since its inception. LEA has published the print version of the conference proceedings and since 2005 has been the publisher of the jo...

This issue of Cognitive Science marks the start of our partnership with Lawrence Erlbaum Associates (LEA). The journal has never been published by LEA before, but in many ways, our relocation feels like a homecoming. In 1976 Roger Schank approached Larry Erlbaum with the idea of forming a cognitive science journal. Mr. Erlbaum was highly receptive, and together with his partner Walter Johnson b...

LEA is a symmetric block cipher proposed in 2014. It uses ARX design and its main advantage is the possibility of a fast software implementation on common computing platforms. In this paper we propose a Differential Fault Analysis attack on LEA. By injecting random bit faults in the last round and in the penultimate round, we were able to recover the secret key by using 258 faulty encryptions i...

We extend the log 2 (N; m; P ) network proposed by Shyy and Lea to base k. We give a unifying proof (instead of three separate cases as done by Shyy and Lea) for the condition of being strictly nonblocking, and a simpler expression of the result. We compare the number of crosspoints for log k (N; m; p) over various k.