This study addresses the problem of finding the range of efficiency for each Decision Making Unit (DMU) considering uncertain data. Uncertainty in the DMU coefficients in each factor (input or output) is captured through interval coefficients (i.e., these are uncertain but bounded). A twophase additive Data Envelopment Analysis (DEA) model for performance evaluation is used, which is adapted to...

Technique of Data Envelopment Analysis (DEA) involves methods conducted for desirable objective management of Decision Making Unit (DMU) that is same increasing of efficiency level. Data envelopment analysis furthermore determines the efficiency level, provides situation, removes inefficiency with evaluated benchmarking information. In this paper the use of the improvement Least-Distance measur...

The traditional data envelopment analysis (DEA) models treat a decision making unit (DMU) as a “black box”, which is often criticized for not considering the inner production mechanism of a production system. The network DEA models developed to overcome this deficiency by considering the internal structure of a DMU have recently gained popularity. The inner data, however, are not generally avai...

It has been reported that theophylline is primarily metabolized via hepatic CYP1A1/2, 2B1/2, and 3A1/2, and 1,3-dimethyluric acid (1,3-DMU) is primarily formed via CYP1A1/2 in rats. Compared with control rats, the expression of CYP1A subfamily, 2B1/2, and 3A subfamily significantly decreased 24 h (24-h KPLPS rats) after intravenous administration of lipopolysaccharide derived from Klebsiella pn...

Tailor-made additives can prove an effective method to prolong the lifetime of metastable forms of pharmaceutical compounds by surface stabilization. Pyrazinamide (PZA) is a pharmaceutical compound with four polymorphic forms. The high temperature γ form, which can be produced by spray drying or sublimation growth, is metastable at room temperature and transforms within days when produced by sp...