Procedures have been developed to label human erythropoietin (Ep) with biotin to detect and isolate the Ep-receptor. The labeling method used the abundant carbohydrate groups on Ep and resulted in biologically active biotin-Ep (b-Ep) containing 8 to 10 biotins per Ep molecule. Specific binding of b-Ep to cells from spleens of mice made anemic by phenylhydrazine injections was demonstrated using...

Inclusive production of D(2010) mesons in deep inelastic scattering has been measured using ep and ep data obtained with the ZEUS detector at HERA using integrated luminosities of 16.7 and 65.2pb, respectively. The decay channel D → Dπ with D → Kπ and corresponding antiparticle decays were used to identify D mesons. The D cross sections in ep and ep interactions agree with NLO QCD predictions, ...

By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data from 1997 to 2013, derived from a cohort of 1 million people randomly sampled to represent all NHI beneficia...

ectopic pregnancy (ep) is the most important cause of maternal death in the first trimester accounting for 9 - 13% of all pregnancy-related deaths (1). despite the use of transvaginal sonography and high sensitive quantitative beta-hcg assays for diagnosis, nearly 40-50% of all eps may be initially misdiagnosed (2). therefore, several biomarkers have been investigated for early diagnosis of ep....

In situ hybridization was used to quantitate the cells that produce erythropoietin (EP) in the renal cortices of mice with varying severities of acute anemia and of mice recovering from severe, acute anemia. The number of EP-producing cells in the renal cortex increased in an exponential manner as hematocrit was decreased. Individual EP-producing cells had very similar densities of silver grain...

Hepatocellular carcinoma (HCC) is believed to originate from cancer stem cells (CSCs). While epithelial cell adhesion molecule (EpCAM) is a marker of normal hepatic stem cells (HSCs), EpCAM+ cells from HCC behave like CSCs. Since HCC mostly develops on a cirrhotic background, we sought to determine whether CSC-like EpCAM+ cells exist in patients with advanced cirrhosis. Both flow cytometry and ...

entrepreneurial passion has been considered as a heart of innovative idea conduction. the present empirical research aimed to investigate factors of students' entrepreneurial passion. in this regard analysis of covariance matrix causal relationship was undertaken. the statistical population comprised of senior and junior undergraduate students as well as graduate students of the university...

The present studies were performed to determine the contribution of EP(2) receptors to renal hemodynamics by examining afferent arteriolar responses to PGE(2), butaprost, sulprostone, and endothelin-1 in EP(2) receptor-deficient male mice (EP(2)-/-). Afferent arteriolar diameters averaged 17.8 +/- 0.8 microm in wild-type (EP(2)+/+) mice and 16.7 +/- 0.7 microm in EP(2)-/- mice at a renal perfus...

The biological activities of PGE(2) are mediated through EP receptors (EP(1)-EP(4)), plasma membrane G protein-coupled receptors that differ in ligand binding and signal-transduction pathways. We investigated gastrointestinal EP(2) receptor expression in adult mice before and after radiation injury and evaluated intestinal stem cell survival and crypt epithelial apoptosis after radiation injury...