نتایج جستجو برای: نقطه epsilon

تعداد نتایج: 31627  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1984
D Tuan I M London

We have mapped the DNase I-hypersensitive sites around the epsilon-globin and c-myc genes in two human leukemia cell lines K562 and HL60. In K562 cells in which the epsilon-globin gene is transcribed, six DNase I-hypersensitive sites are found in 6 kilobases (kb) of upstream flanking DNA; in HL60 cells in which the c-myc gene is expressed, two DNase I-hypersensitive sites are observed in 2 kb o...

Journal: :Alzheimer disease and associated disorders 2008
Valéria Santoro Bahia Fernando Kok Suely Nagahashi Marie Sueli Oba Shinjo Paulo Caramelli Ricardo Nitrini

Alzheimer disease (AD) is the most frequent cause of dementia in Western countries. Putative genetic risk factors for AD are polymorphisms in the apolipoprotein E (APOE) gene and in the low-density lipoprotein receptor-related protein (LRP) gene. Our objective was to investigate the role of the APOE coding region polymorphisms epsilon 2, epsilon 3, and epsilon 4 and APOE promoter variants A/T a...

Journal: :Biophysical journal 2003
Turgut Baştuğ Serdar Kuyucak

Using both analytical solutions obtained from simplified systems and numerical results from more realistic cases, we investigate the role played by the dielectric constant of membrane proteins epsilon(p) and pore water epsilon(w) in permeation of ions across channels. We show that the boundary and its curvature are the crucial factors in determining how an ion's potential energy depends on the ...

Journal: :European Physical Journal C 2023

We investigate the possibility to describe quark mass hierarchies as well CKM mixing matrix without fine-tuning in a flavour model with modular $A_4$ symmetry. The are considered vicinity of fixed point $\tau = \omega \equiv \exp({i\,2\pi/3})$ (the left cusp fundamental domain group), $\tau$ being VEV modulus. involves forms level 3 and weights 6, 4 2, contains eight constants, only two which, ...

Journal: :Blood 1997
R Morosetti D J Park A M Chumakov I Grillier M Shiohara A F Gombart T Nakamaki K Weinberg H P Koeffler

Human C/EBP epsilon is a newly cloned CCAAT/enhancer-binding transcription factor. Initial studies indicated it may be an important regulator of human myelopoiesis. To elucidate the range of expression of C/EBP epsilon, we used reverse transcription-polymerase chain reaction (RT-PCR) analysis and examined its expression in 28 hematopoietic and 14 nonhematopoietic cell lines, 16 fresh myeloid le...

Journal: :The Journal of Experimental Medicine 1996
W P Fung-Leung J De Sousa-Hitzler A Ishaque L Zhou J Pang K Ngo J A Panakos E Chourmouzis F T Liu C Y Lau

The high-affinity receptor for immunoglobulin (Ig) E (Fc epsilon RI) on mast cells and basophils plays a key role in IgE-mediated allergies. Fc epsilon RI is composed of one alpha, one beta, and two gamma chains, which are all required for cell surface expression of Fc epsilon RI, but only the alpha chain is involved in the binding to IgE. Fc epsilon RI-IgE interaction is highly species specifi...

Journal: :Physical review 2021

In a recent paper, it was shown that, under the action of lateral van der Waals (vdW) force due to perfectly conducting corrugated surface, neutral anisotropic polarizable particle in vacuum can be attracted not only nearest corrugation peak but also valley or an intermediate point between and valley, with such behaviors called peak, regimes, respectively. present we investigate how these regim...

Journal: :The Journal of Cell Biology 1993
K Gundersen J R Sanes J P Merlie

The effects of denervation were investigated in mice with transgenes containing promoter elements from the muscle acetylcholine receptor epsilon- and alpha-subunit genes. The promoter sequences were coupled to a nuclear localization signal-beta-galactosidase fusion gene (nlacZ) as a reporter. While many postsynaptic specializations form in the embryo, expression of the epsilon subunit is induce...

Journal: :Blood 2001
H Nakajima J N Ihle

Granulocyte colony-stimulating factor (G-CSF) is a major cytokine that regulates proliferation and differentiation of myeloid cells, although the underlying mechanisms by which G-CSF controls myeloid differentiation are largely unknown. Differentiation of hematopoietic cells is regulated by lineage-specific transcription factors, and gene-targeting studies previously revealed the critical roles...

Journal: :Circulation research 2006
Martin Jabůrek Alexandre D T Costa Jana R Burton Cinthia L Costa Keith D Garlid

Mitochondria are key mediators of the cardioprotective signal and the mitochondrial ATP-sensitive K+ channel (mitoK(ATP)) plays a crucial role in originating and transmitting that signal. Recently, protein kinase C epsilon (PKC epsilon) has been identified as a component of the mitoK(ATP) signaling cascade. We hypothesized that PKC epsilon and mitoK(ATP) interact directly to form functional sig...

200420052006200720082009201020112012201320142015201620172018201920202021202220230400800

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید