نتایج جستجو برای: نظریه منبع محور rbv
تعداد نتایج: 69073 فیلتر نتایج به سال:
BACKGROUND The optimal treatment for respiratory syncytial virus (RSV) infection in adult immunocompromised patients is unknown. We assessed the management of RSV and other non-influenza respiratory viruses in Midwestern transplant centers. METHODS A survey assessing strategies for RSV and other non-influenza respiratory viral infections was sent to 13 centers. RESULTS Multiplex polymerase ...
BACKGROUND/OBJECTIVE Genetic polymorphisms in the inosine triphosphatase (ITPA) gene have been associated with the protection from early ribavirin(RBV)-induced hemolytic anemia among patients with chronic hepatitis C virus (HCV) infection. The aim of the present study was to investigate the association between the functional ITPA variants and hematological side effects during antiviral therapy ...
UNLABELLED Two functional variants in the inosine triphosphatase (ITPA) gene causing inosine triphosphatase (ITPase) deficiency protect against ribavirin (RBV)-induced hemolytic anemia and the need for RBV dose reduction in patients with genotype 1 hepatitis C virus (HCV). No data are available for genotype 2/3 HCV. We evaluated the association between the casual ITPA variants and on-treatment ...
• A dominant theoretical paradigm in academic strategic management circles is the Resource-Based View (RBV). This paper reviews the literature of this position and the extent to which the RBV may be seen as a source of practical guidance for managers seeking competitive advantage and strategic success. • The theories of management academics should be of practical value to managers, otherwise su...
انتخاب شریک تجاری یکی از موضوعات مهم و اولیه در ایجاد اتحادها است و به عنوان پیش شرط موفقیت یک اتحاد به شمار می‌رود. به موازات بنگاه ها و شرکت هایی که برای انتخاب شرکای راهبردی خود، معیارها و مکانیزم های تصمیم گیری در خصوص این موضوع را در فرایندهای عملیاتی خود برجسته کرده اند، محققان مدیریت نیز به توسعه نظریه ها و معیارهای انتخاب شریک پرداخته اند. رویکردهای نظری به انتخاب متحد تجاری را می‌توان ...
هدف: هدف از این مقاله، بررسی مسائلِ اخلاقیِ مطرح در مدیریت اطلاعات از منظر چهار نظریه ی عمده ی اخلاق هنجاری (نظریه های نتیجه محور، وظیفه محور، حق محور و فضیلت محور) است. روش: این پژوهش با استفاده از روش تحلیلی مفهومی انجام پذیرفت. یافته ها: در این مقاله نشان داده می شود که چگونه می توان نظریه های اخلاقی را برای حل مسائل و چالش های انضمامی مدیریت اطلاعات به کار گرفت. همچنین مشخص می شود که هر یک ...
OBJECTIVE Hepatitis E virus (HEV) infection can take chronic courses in immunocompromised patients potentially leading to liver cirrhosis and liver failure. Ribavirin (RBV) is currently the only treatment option for many patients, but treatment failure can occur which has been associated with the appearance of a distinct HEV polymerase mutant (G1634R). Here, we performed a detailed analysis of ...
BACKGROUND Occurrence of hypotension during hemodialysis in nearly 20-30% of patients, shows is the necessity of continuous monitoring the patients' blood pressure during hemodialysis. Since directly and non-invasively continuous blood pressure monitoring, is not easy, finding a parameter related to blood pressure, for indirect monitoring is of great value. Related blood volume (RBV) is one of ...
INTRODUCTION AND AIM There is almost no data regarding the efficacy of direct acting antivirals (DAAs) therapy in Brazil. The aim of this historical cohort study is to describe the sustained virologic response (SVR) rate among real-world compensated chronic hepatitis C patients in three hepatology centers from Southern Brazil. MATERIALS AND METHODS Patients were included if they had at least ...
Background: Danoprevir (RG7227) is an inhibitor of the HCV NS3/4A protease. In two Phase Ib studies of treatment-naive patients with chronic HCV genotype 1 infection, danoprevir administration for 14 days was associated with HCV RNA median reduction reaching 3.8 log10 in monotherapy and 5.7 log10 in combination therapy with pegylated interferon (PEG-IFN)-a2a (40 KD) plus ribavirin (RBV). After ...
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