A series of pyridine ether PPAR agonists were synthesized through an ADDP and PS-PPh3 modified Mitsunobu protocol, which eliminated significant by-product formation. This method proved to be versatile, efficient and amenable to parallel synthesis.

background: acute blood purification (abp) therapy is used regularly in the clinical setting and reportedly alleviates organ failure associated with severe systemic inflammatory responses, leading to reduced mortality. the present study aimed to determine whether there is a difference in efficacy between polysulfone (ps) membranes, which are currently used regularly in the clinical setting, and...

Let Cg be a smooth projective irreducible curve over C of genus g ≥ 1 and let {p1, p2, . . . , ps} be a set of distinct points on Cg. We fix a nonnegative integer l and denote by Mg(p, λ) the moduli space of parabolic semistable vector bundles of rank r with trivial determinant and fixed parabolic structure of type λ = (λ1, λ2, . . . , λs) at p = (p1, p2, . . . , ps), where each weight λi is in...

Hf-phosphinoamide cation complexes behave as metal-based frustrated Lewis pairs and bind one or two equivalent of CO2 and in as well can activate CO2 in a bimetallic fashion to give a pseudo-tetrahedral P2CO2 fragment linking two Hf centres.

Recently, there has been a growing interest in learning approaches that combine two phases: an initial problem-solving phase followed by an instruction phase (PS-I). Two often cited examples of instructional approaches following the PS-I scheme include Productive Failure and Invention. Despite the growing interest in PS-I approaches, to the best of our knowledge, there has not yet been a compre...

An array of SeaSonde HF radars has been deployed along the Oregon coast by P. M. Kosro of the College of Oceanic and Atmospheric Sciences, OSU. Data from a two-site HF array, which provides measurements of surface currents over a region about 50 km square, have been collected since November 1997. This project is aimed initially at developing and applying, in cooperation with Kosro, methods for ...

The thermal unimolecular dissociation of CH3F was studied in shock waves by monitoring the UV absorption of a dissociation product identified as CH2F. It is concluded that, under conditions applied, the formation of this species corresponds to a minor, spin-allowed, dissociation channel of about 3% yield. Near to the low-pressure limit of the reaction, on the other hand, the energetically more ...