Centrioles play a crucial role in mitotic spindle assembly and duplicate precisely once per cell cycle. In worms, flies, and humans, centriole assembly is dependent upon a key regulatory kinase (ZYG-1/Sak/Plk4) and its downstream effectors SAS-5 and SAS-6. Here we report a role for protein phosphatase 2A (PP2A) in centriole duplication. We find that the PP2A catalytic subunit LET-92, the scaffo...

Effectively managing and reporting the vast amount of data collected in a distributed Client/Server environment is not only complex but can be overwhelming. This paper will discuss how SAS@ was used to integrate data from multiple vendor tools and provide an effective network management collection and reporting capability. Discussed will be how base SAS, SAS/CpE@ and SAS/GRAPH@, integrated thro...

Although the Multi-Input and Multi-Output (MIMO) communication systems provide very high data rates with low error probabilities, these advantages are obtained at the expense of having high signal processing tasks and the hardware cost, e.g. expensive Analog-to-Digital (A/D) converters. The increased hardware cost is mainly due to having multiple Radio Frequency (RF) chains (one for each antenn...

Recent advances in small-angle scattering (SAS) experimental facilities and data analysis methods have prompted a dramatic increase in the number of users and of projects conducted, causing an upsurge in the number of objects studied, experimental data available and structural models generated. To organize the data and models and make them accessible to the community, the Task Forces on SAS and...

BACKGROUND Data from BreastScreen Australia Screening and Assessment Services (SAS) for 2002-2010 were analysed to determine whether some SAS characteristics were more conducive that others to high screening performance, as indicated by high priority performance indicators and standards. MATERIALS AND METHODS Indicators investigated related to: numbers of benign open biopsies, screen-detected...

PURPOSE To examine the subarachnoid space (SAS) of eyes with pathologic myopia and analyze the characteristics of the SAS and the surrounding tissues by swept-source optical coherence tomography (OCT). METHODS One hundred thirty-three eyes of 76 patients with pathologic myopia (spherical equivalent refractive error of >-8.00 diopters (D) or an axial length >26.5 mm) and 32 eyes of 32 subjects...

BACKGROUND Cardiovascular diseases leading to pacemaker implantations are suspected of being associated with a high rate of undiagnosed sleep apnea syndrome (SAS). We sought to determine the prevalence and consequences of SAS in pacemaker patients according to pacing indications: heart failure, symptomatic diurnal bradycardia, and atrioventricular block. METHODS AND RESULTS Ninety-eight conse...