In this paper, we present polymerization condition at which conductive polymer poly(3,4-ethylenedioxytheophene) (PEDOT) known as bio-compatible material was grown on the MEA(Multi Electrode Array) electrodes and successively reduced the impedance of MEA electrodes. Proposed polymerization condition was selected to be similar to neural stimulation condition which is safe to neurons, so polymeriz...

We have shown that copper amplifies prostaglandin E2 (PGE2) stimulation of luteinizing hormone-releasing hormone (LH-RH) from explants of the median eminence area (MEA) and that this process is calcium-dependent. Since a Ca-cAMP pathway has been implicated in PGE2 action on the LH-RH neuron, in this study we wished to ascertain if copper exerts its effect on the PGE2 receptor or on a postrecept...

Studying brain function and its local circuit dynamics requires neural interfaces that can record and stimulate the brain with high spatiotemporal resolution. Optogenetics, a technique that genetically targets specific neurons to express light-sensitive channel proteins, provides the capability to control central nervous system neuronal activity in mammals with millisecond time precision. This ...

BACKGROUND Tobacco smoking is the main health-care problem in the world. Evaluation of scientific output in the field of tobacco use has been poorly explored in Middle Eastern Arab (MEA) countries to date, and there are few internationally published reports on research activity in tobacco use. The main objectives of this study were to analyse the research output originating from 13 MEA countrie...

Reduced antiplatelet effect of clopidogrel assessed with multiple electrode aggregometry (MEA) and vasodilator stimulated phosphoprotein-phosphorylation (VASP-P) assay has been proven to predict major adverse cardiovascular events (MACE) after coronary stenting. So far no consecutive registry has evaluated the usefulness of different adenosine diphosphate-based platelet function tests to predic...

Copulas are a general tool for assessing the dependence structure of random variables. Important properties as well as a number of examples are discussed, including Archimedean copulas and the Marshall-Olkin copula. As measures of the dependence we consider linear correlation, rank correlation, the coefficients of tail dependence and association. Copulas are a tool for modeling and capturing th...