BACKGROUND Angiogenesis has been implicated in the pathogenesis of idiopathic interstitial pneumonia (IIP). The aim of this study was to examine the relationship between plasma concentrations of the angiogenic cytokines interleukin 8 (IL-8), vascular endothelial growth factor (VEGF), and endothelin-1 (ET-1) and clinical parameters of disease progression over a 6 month period to identify potenti...

Pulmonary fibrosis is the formation of fibrous tissue as a reaction or a repair process in the lung. It is the main cause of severe morbidity and mortality in interstitial lung disease (ILD). Pathogenesis in most ILDsis triggered by exposition to exogenous factors, such as asbestos and radiation, or endogenous factors, such as auto-immune disease and drugs. However, in a subgroup of ILD, the id...

A commercial red tilapia farm was diagnosed with Streptococcus agalactiae infection using histopathology, microbiology and immunohistochemistry. One hundred fish were randomly taken from different weight/age groups including broodstock, market fish (larger than 150 g), on-growing fish between 20 and 150 g, juveniles and larvae. Fish were clinically examined, anaesthetised and necropsied. Sample...

Context. The progenitor mass of type IIP supernova can be determined from either hydrodynamic modeling of the event or pre-explosion observations. Aims. To compare these approaches, we determine parameters of the sub-luminous supernova 2005cs and estimate its progenitor mass. Methods. We compute the hydrodynamic models of the supernova to describe its light curves and expansion velocity data. R...

Este estudo envolve a preparação de um polímero orgânico-inorgânico impresso com íon (IIP) para o enriquecimento seletivo de Ni em soluções aquosas com posterior determinação por GF AAS. A rede polimérica híbrida foi preparada a partir de uma mistura do monômero funcional, 2-aminoetil-3-aminobutilmetildimetoxissilano e tetraetoxissilano como agente de ligação cruzada, contendo Ni e brometo de c...

Information on how the patient's interpersonal problems predict alliance development during long-term therapy is lacking. The aim of this study was to explore how the patient's pre-treatment interpersonal problems predict the development of alliance in long-term psychotherapy. Altogether 128 adult outpatients experiencing mood or anxiety disorder were assigned to long-term psychodynamic psychot...

Cystic fibrosis (CF) lungs harbor a complex community of interacting microbes, including pathogens like Pseudomonas aeruginosa. Meta-taxogenomic analysis based on V5-V6 rrs PCR products of 52 P. aeruginosa-positive (Pp) and 52 P. aeruginosa-negative (Pn) pooled DNA extracts from CF sputa suggested positive associations between P. aeruginosa and Stenotrophomonas and Prevotella, but negative ones...

BACKGROUND Molecular methods based on phylogenetic differences in the 16S rRNA gene are able to characterise the microbiota of the respiratory tract in health and disease. OBJECTIVES Our goals were (1) to characterise bacterial communities in lower and upper airways of patients with interstitial lung disease (ILD) and (2) to compare the results with the microbiota of patients with Pneumocysti...