BACKGROUND/AIM Human mesenchymal stem cells (hMSCs) are thought to be one of the most reliable stem cell sources for a variety of cell therapies. This study investigated the anti-tumor effect of human adipose tissue-derived mesenchymal stem cells (hAT-MSCs) on EL4 murine T-cell lymphoma in vitro and in vivo. MATERIALS AND METHODS The growth-inhibitory effect of hAT-MSCs on EL4 tumor cells was...

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) may serve as a new assay for drug testing in a human context, but their validity particularly for the evaluation of inotropic drug effects remains unclear. In this blinded analysis, we compared the effects of 10 indicator compounds with known inotropic effects in electrically stimulated (1.5 Hz) hiPSC-CM-derived 3-dimensional...

In this paper, we introduce the new definitions and fixed-point theorems for \((\hat{\alpha}-\hat{\psi})\)-Geraghty contraction with an aid of simulation function \(\zeta:[0, \infty) \times[0, \rightarrow \mathbb{R}\) in generalized metric space satisfying following condition:if \(\exists \hat{\beta} \in \mathcal{F}\) such that all \(r, s \mathfrak{X}\), then have\(\zeta[\hat{\alpha}(r, s)(d(\m...

[Purpose] This study aimed to determine the effect of the type of hat worn on balance, eye-hand coordination, and visual perception of normal adults. [Subjects and Methods] Eight healthy male (20.87±1.95 years, 171.38±4.03 cm, 60.75±7.94 kg) and seven female (20.14±0.89 years, 160.57±5.25 cm, 57.14±7.92 kg) university students participated in this study. Balance ability, eye-hand coordination, ...

We report on the discovery of HAT-P-10b, the lowest mass (0.46 ± 0.03MJ) transiting extrasolar planet (TEP) discovered to date by transit searches. HAT-P-10b orbits the moderately bright V=11.89 K dwarf GSC 02340-01714, with a period P = 3.7224690 ± 0.0000067 d, transit epoch Tc = 2454729.90631± 0.00030 (BJD) and duration 0.1100 ± 0.0015d. HAT-P-10b has a radius of 1.05 −0.03RJ yielding a mean ...

BACKGROUND Socio-cultural and economic factors constitute real barriers for uptake of screening and treatment of Human African Trypanosomiasis (HAT) in the Democratic Republic of Congo (DRC). Better understanding and addressing these barriers may enhance the effectiveness of HAT control. METHODS We performed a qualitative study consisting of semi-structured interviews and focus group discussi...