STEPHEN M. WIENER,1 ROBERT F. HOYT, JR.,2 JOHN R. DELEONARDIS,2 RANDALL R. CLEVENGER,2 KENNETH R. JEFFRIES,2 KUNIO NAGASHIMA,3 MYRNA MANDEL,4 JENNIE OWENS,5 MICHAEL ECKHAUS,5 ROBERT J. LUTZ,6 AND BRIAN SAFER1 1Molecular Hematology Branch and 2Laboratory of Animal Medicine and Surgery, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda 20892; 3Laboratory of Cell a...

NICOLA L. JONES,1,2,3 AVINASH ISLUR,1 RIZWAN HAQ,4 MARIOLA MASCARENHAS,1 MOHAMED A. KARMALI,2 MARY H. PERDUE,5 BRENT W. ZANKE,4 AND PHILIP M. SHERMAN1,2,3 1Research Institute, Hospital for Sick Children, and Departments of 2Molecular Microbiology and Medical Genetics and 3Pediatrics, University of Toronto, Toronto M5G 1X8; 4Department of Medicine, University of Toronto, Princess Margaret Hospit...

Gupta, Gaurav, Jane A. Cases, Li She, Xiao-Hui Ma, Xiao-Man Yang, Meizu Hu, Jeanie Wu, Luciano Rossetti, and Nir Barzilai. Ability of insulin to modulate hepatic glucose production in aging rats is impaired by fat accumulation. Am J Physiol Endocrinol Metab 278: E985– E991, 2000.—Increased total fat mass (FM) and visceral fat (VF) may account in part for age-associated decrease in hepatic insul...

Moore, Beverley A., Gerald P. Morris, and Stephen Vanner. A novel in vitro model of Brunner’s gland secretion in the guinea pig duodenum. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G477–G485, 2000.—A novel in vitro model that combined functional and morphological techniques was employed to directly examine pathways regulating Brunner’s gland secretion in isolation from epithelium. In vit...

Yamashita, Masatomo, and Mamoru Yamashita. Hyperbaric oxygen treatment attenuates cytokine induction after massive hemorrhage. Am J Physiol Endocrinol Metab 278: E811–E816, 2000.—We investigated the effect of hyperbaric oxygen treatment (HBO) on cytokine induction after hemorrhage, because hypoxia induces cytokines in vitro. Chronically cannulated conscious rats were subjected to 40 ml/kg of he...

AREND BONEN,1 DRAGANA MISKOVIC,1 MIO TONOUCHI,1 KATHLEEN LEMIEUX,2 MARIEANGELA C. WILSON,3 ANDRÉ MARETTE,2 AND ANDREW P. HALESTRAP3 1Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L 3G1; 2Department of Physiology, Lipid Research Unit, Hospital Research Center, Laval University, Quebec, Canada G1V 4G2; and 3Department of Biochemistry, University of Bristol, Bristol BS8 1T...

Hansen, Lene, Bolette Hartmann, Thue Bisgaard, Hitoshi Mineo, Peer N. Jørgensen, and Jens J. Holst. Somatostatin restrains the secretion of glucagon-like peptide-1 and -2 from isolated perfused porcine ileum. Am J Physiol Endocrinol Metab 280: E1010–E1018, 2000.— Suspecting that paracrine inhibition might influence neuronal regulation of the endocrine L cells, we studied the role of somatostati...