objective(s):solid dispersion formulation is the most promising strategy to improve oral bioavailability of poorly water soluble drugs. the aim of this study was to compare the effect of polyvinylpyrrolidone k30 (pvp) and poloxamer-188 (plx) as carrier in solid dispersion formulations of celecoxib (clx). materials and methods: solid dispersions of clx:pvp or clx:plx were prepared at different r...

background:   objective: we evaluated the icsi outcome in our program for (htlv-1) serodiscordant couples (sdcs) with the female infected in comparison with control group.   materials and methods: this study was performed between 2007 and 2011 in novin infertility treatment center (mashhad, iran). we examined 32 icsi cycles of htlv-1 infected women in comparison with an age matched control grou...

human resource productivity is an important subject in theory and practice, so increase of productivity is the first priority in most of organizations. the main purpose of most organizations is creating value for their shareholders. so it is necessary to understand effect of human resource productivity in achieving this goal and find the obstacles. the purpose of this research is examining the ...

assesment of health related quality of life (hrql) is increasingly recognized as an important part of the patient care in asthma. we aimed to evaluate the effect of personality disorders (pds) on hrql and the severity of disease in asthmatic patients. ninety seven consecutive patients with asthma and ninety healthy controls were included. all  patients  completed  a  short  form-36  health  sur...

new derivatives of 2-[2-(2-chlorophenoxy)phenyl]-1,3,4-oxadiazole as candidates for agonistic effect on benzodiazepine receptors were synthesized. conformational analysis and superimposition of energy minima conformers of the novel compounds on estazolam, a known benzodiazepine agonist, revealed that the main proposed benzodiazepine pharmacophores were well matched. in pharmacological evaluatio...

this research is about analysis of relation between trust and organizational commitment of personnel. statistic social in this research is the personnel of social welfare organization of qom state and education organization of qom state and statical sample is consist of 35 employees from social welfare organization and 54 employees from education organization of qom state. in analysis of organi...

the 17-4ph alloy is a martensitic stainless steel with 3–5 wt% cu, strengthened by the precipitation hardening. due to excellent mechanical properties, corrosion resistance and ease of heat treatment, this alloy has unique applications in nuclear power plants and marine constructions. in this paper, the influence of ageing heat treatment, solution annealing followed by ageing at 480, 550 and 62...

beta-2 adrenoceptors in blood vessels are one of the active factors that play a role in regulation of tissue blood flow. in diabetic angiopathy, responsiveness of these receptors is decreased, while that is increased in inflammation. according to these opposite effects, the aim of this study was to investigate the vasodilatory response of knee joint blood vessels to salbutamol (beta-2 adrenocep...

this study was conducted to determine water stress tolerance of two iranian dudaim melons (kerman & birjand) and one iranian muskmelon (samsoury). throughout the experiment, three different levels of irrigation with three irrigation starting points (-50, -65 and -75 cb of matric potential) were employed. results indicated that water stress significantly affected yield, firmness, fruit sugars as...