introduction: recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (ms). molecular target therapy studies in ms have revealed that connexin-43 (cx43) and aquaporin-4 (aqp4) contents of astrocytes undergo expression alteration. fluoxetine had some effects in ms patients unrelated to its known antidep...

[1] We perform two 23 year simulations using a regional climate model coupled with the National Center for Atmospheric Research Community Land Model version 3.5 (RegCM‐CLM) to investigate land‐atmosphere coupling in the continental United States during the cold season (October–April) and the role of soil water phase. One simulation allows the land surface to interact freely (RunI) while the oth...

BACKGROUND & OBJECTIVES In the Carpathian Basin, the most northern populations of Phlebotomus (sandfly) species, including the two studied species (Phlebotomus mascittii and Phlebotomus neglectus), are reported from central Hungary. The most important limiting factor of the distribution of Phlebotomus species in the region is the annual minimum temperature which may be positively affected by th...

Introduction: Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS). Molecular target therapy studies in MS have revealed that connexin-43 (Cx43) and Aquaporin-4 (AQP4) contents of astrocytes undergo expression alteration. Fluoxetine had some effects in MS patients unrelated to its known antidep...

The confluence of factors driving urban growth is highly complex, resulting from a combination of ecological and social determinants that co-evolve over time and space. Identifying these factors and quantifying their impact necessitates models that capture both why urbanization happens as well as where and when it happens. Using a database that links five satellite images spanning 1976–2001 to ...

evaporation. Taking the mean density and Bond albedo of a typical Vulcanoid to be the same as that of Mercury, we ®nd that objects with radii z satisfying 0:1 ( z ( 50 km can evade both drag and evaporation in the Vulcanoid belt. This is one of the most dynamically stable regimes in the entire Solar System. If further searches do not detect any intra-mercurial objects, this is a strong indicato...

This study aimed to investigate the effects of polymorphisms of the flavin-containing mono-oxygenase 3 (FMO3) and flavin-containing mono-oxygenase 6 (FMO6) genes on the pharmacokinetics of sulindac sulfide, the active metabolite of sulindac, in patients with preterm labor. Ten single-nucleotide polymorphisms (SNPs) were genotyped, and plasma sulindac sulfide concentrations were measured at 0, 1...