نتایج جستجو برای: مدل ارزیابی عمومی caf

تعداد نتایج: 247615  

Journal: :The Journal of biological chemistry 1998
K Marheineke T Krude

We characterized changes of nucleosome assembly activity, intracellular localization, and reversible phosphorylation of the human chromatin assembly factor CAF-1 during the somatic cell division cycle. HeLa cells were synchronized in the G1, S, G2, and M phases of the cell cycle. All three subunits of human CAF-1 (p150, p60, and p48) are present during the entire cell cycle. In interphase, p150...

Journal: :Development 1991
I Flamme K Schulze-Osthoff H J Jacob

The chorioallantoic membrane (CAM) is one of the most vascularized tissues in the chicken embryo. Capillary growth proceeds until day 10 of development and thereafter abruptly regresses. As it is generally accepted that the formation of new blood vessel is regulated by growth factors, we have investigated the presence of angiogenic and mitogenic factors in the chicken chorioallantois. In the pr...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Ming-Heng Wu Hsiao-Chin Hong Tse-Ming Hong Wei-Fan Chiang Ying-Tai Jin Yuh-Ling Chen

PURPOSE Carcinoma-associated fibroblasts (CAFs) in tumor stroma play an important role in tumor progression and have been associated with a poor prognosis in oral squamous cell carcinoma (OSCC). However, how CAFs influence OSCC malignancy and whether normalizing CAFs inhibits cancer progression remain unclear. EXPERIMENTAL DESIGN The relationship between the expression of Galectin-1 (Gal-1) a...

Journal: :Biophysical chemistry 2006
M P Evstigneev K A Rybakova D B Davies

(1)H NMR spectroscopy (500 MHz) has been used to quantify the complexation of the antibacterial antibiotic Norfloxacin (NOR) with DNA in the presence of Caffeine (CAF). Separate studies have been made for the self-association of NOR, its hetero-association with CAF and complexation with a model self-complementary DNA tetramer, 5'-d(TpGpCpA), in order to determine the equilibrium parameters (ind...

Journal: :Circulation research 2010
Alexandra Belus Nicoletta Piroddi Cecilia Ferrantini Chiara Tesi Olivier Cazorla Luana Toniolo Maurice Drost Giulia Mearini Lucie Carrier Alessandra Rossi Alessandro Mugelli Elisabetta Cerbai Jolanda van der Velden Corrado Poggesi

RATIONALE Chronic atrial fibrillation (cAF) is associated with atrial contractile dysfunction. Sarcomere remodeling may contribute to this contractile disorder. OBJECTIVE Here, we use single atrial myofibrils and fast solution switching techniques to directly investigate the impact of cAF on myofilament mechanical function eliminating changes induced by the arrhythmia in atrial myocytes membr...

Journal: :Experimental Gerontology 2011
Marlon Régis Leite Ethel A. Wilhelm Cristiano R. Jesse Ricardo Brandão Cristina Wayne Nogueira

In this study, the effects of caffeine (CAF) and SCH58261, a selective A(2A) receptor antagonist, on memory impairment and oxidative stress generated by aging in rats were investigated. Young and aged rats were treated daily per 10 days with CAF (30 mg/kg p.o.) or SCH58261 (0.5mg/kg, p.o.) or vehicle (1 ml/kg p.o.). Rats were trained and tested in a novel object recognition task. After the beha...

2012
Wallace H. Liu Sarah C. Roemer Alex M. Port Mair E.A. Churchill

Anti-silencing function 1 (Asf1) and Chromatin Assembly Factor 1 (CAF-1) chaperone histones H3/H4 during the assembly of nucleosomes on newly replicated DNA. To understand the mechanism of histone H3/H4 transfer among Asf1, CAF-1 and DNA from a thermodynamic perspective, we developed and employed biophysical approaches using full-length proteins in the budding yeast system. We find that the C-t...

2010
Andrew Myers

In modern high performance computers there is a trend towards a hybrid architecture. This hybrid architecture features distributed nodes, each of which contains multiple cores, over which memory is shared. A current challenge in HPC (High Performance Computing) is to find solutions which make the best possible use of hybrid architectures. One possible solution is the use of PGAS (Partitioned Gl...

Journal: :Journal of virology 1971
M Muramatsu M Homma

A trypsin-like protease which is responsible for activation of Sendai virus was found in the chorioallantoic fluid (CAF) of embryonated chicken eggs. Treatment of the inactive form of Sendai virus, grown in LLC-MK2 cells, with CAF enhanced both hemolytic activity and infectivity for the cells. Soybean trypsin inhibitor restrained the enhancing activity of CAF. These results indicate that CAF co...

Journal: :Journal of applied physiology 2002
Farah S L Thong Terry E Graham

The caffeine-induced impairment of insulin action is commonly attributed to adenosine receptor (AR) antagonism in skeletal muscle. However, epinephrine, a potent inhibitor of insulin actions, is increased after caffeine ingestion. We tested the hypothesis that the insulin antagonistic effects of caffeine are mediated by epinephrine, and not by AR antagonism, in seven healthy men. On four separa...

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