Background and aims: IL-22 is an alpha- helical cytokine. IL-22 binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells. L-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. The aim of this study was to i...

Background: Recent studies have shown that cytokines have an important role in the pathogenesis of inflammatory diseases and can be used as prognostic markers. Objective: To evaluate the IL-6/IL-10 ratio in patients with Inherited Epidermolysis Bullosa (EB) as a prognostic marker. Methods: Serum levels of IL-6 and IL-10 were measured in 13 patients with recessive dystrophic EB (RDEB) as well as...

The linear filters characterized by a state-variable realization given by matrices with nonnegative entries (called positive filters) are heavily restricted in their achievable performance. Nevertheless, such filters are the only choice when dealing with the charged coupled device MOS technology of charge routing networks (CRNs), because nonnegativity is a consequence of the underlying physical...

On the transferability of time-lagged independent components between similar molecular dynamics systems Alexander S. Moffett1 and Diwakar Shukla1, 2, 3 Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana IL, 61801 USA Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana IL, 61801 USA Department of ...

We present and describe CIF-CK — a social agent architecture that models reasoning about persistent social interactions to improve narrative engagement and play experience for human interactors. The architecture is inspired by McCoy et al’s Comme il-Faut (CiF) architecture that represented rich social interactions between agents that included feelings, social and relationship contexts, and long...