نتایج جستجو برای: مادۀ 251 قت

تعداد نتایج: 7549  

Journal: :The Journal of biological chemistry 1976
R Kleppe T Sekiya P C Loewen K Kleppe K L Agarwal H Büchi P Besmer M H Caruthers P J Cashion M Fridkin E Jay A Kumar R C Miller K Minamoto A Panet U L RajBhandary B Ramamoorthy N Sidorova T Takeya J H van de Sande H G Khorana

The DNA duplex corresponding to the entire length (126 nucleotides) of the precursor for an Escherichia coli tyrosine tRNA has been synthesized. Duplex [I] (Sekiya, T., Besmer, P., Takeya, T., and Khorana, H. G.(1976) J. Biol. Chem. 251, 634-641), corresponding to the nucleotide sequence 1-26, containing single-stranded ends and carrying one appropriately labeled 5'-phosphate group, was joined ...

Journal: :Basic & clinical pharmacology & toxicology 2008
Nina L Cluny Robert J Naylor Brian A Whittle Farideh A Javid

The effect of cannabinoids on motion-induced emesis is unknown. The present study investigated the action of phytocannabinoids against motion-induced emesis in Suncus murinus. Suncus murinus were injected intraperitoneally with either cannabidiol (CBD) (0.5, 1, 2, 5, 10, 20 and 40 mg/kg), Delta(9)-tetrahydrocannabinol (Delta(9)-THC; 0.5, 3, 5 and 10 mg/kg) or vehicle 45 min. before exposure to ...

2015
Wan Soo Kim Sang Soo Lee Chang Min Lee Hong Jun Kim Chang Yoon Ha Hyun Jin Kim Tae Hyo Kim Woon Tae Jung Ok Jae Lee Jeong Woo Hong Hyun Seon You Hyun Chin Cho

BACKGROUND The risk of anti-tuberculosis (TB) drug-induced liver injury (DILI) in patients with chronic viral hepatitis (CVH) is not clear. The aim of this study was to investigate incidence and risk factors associated with TB DILI in CVH and non-CVH patients. METHODS Retrospectively, a total of 128 CVH patients who received anti-TB medication from January 2005 to February 2014 were reviewed....

Journal: :Journal of Korean Medical Science 2000
Y. K. Hong Y. A. Joe Y. J. Yang K. S. Lee B. C. Son S. S. Jeun D. S. Chung K. K. Cho C. K. Park M. C. Kim H. K. Kim W. K. Yung J. K. Kang

We investigated the antineoplastic potentials of recombinant adenovirus containing wild-type p53 cDNA (Ad5CMV-p53) for malignant gliomas. In four human glioma cell lines (U-251 and LG expressing endogenous mutant p53, and U-87 and EFC-2 expressing wild-type p53) and two rat glioma cell lines (9L and C6, each expressing mutant and wild-type p53), gene transfer efficiency determined by X-gal stai...

2012
Hae Yeon Kang Sang Gyun Kim Mi Kyung Lee Joo Sung Kim Hyun Chae Jung In Sung Song

Previous studies suggested that polymorphisms of proinflammatory cytokine genes are important host genetic factors in Helicobacter pylori infection. The present study evaluated whether IL-8-251 polymorphism affected H. pylori eradication rate and to investigate the effect of H. pylori eradication on angiogenesis and the inflammatory process according to the IL-8-251 polymorphism. A total of 250...

Journal: :The Journal of biological chemistry 2009
Yi-Ju Chen Carmen Dominguez-Brauer Zebin Wang John M Asara Robert H Costa Angela L Tyner Lester F Lau Pradip Raychaudhuri

The Forkhead box M1 (FoxM1) transcription factor is critical for expression of the genes essential for G(1)/S transition and mitotic progression. To explore the cell cycle regulation of FoxM1, we examined the phosphorylation profile of FoxM1. Here, we show that the phosphorylated status and the activity of FoxM1 increase as cells progress from S to G(2)/M phases. Moreover, dephosphorylation of ...

Journal: :Biochemical and Biophysical Research Communications 2009

2010
Bruce A. Maxwell

This course prepares students to apply computational approaches to data analysis and visualization to real information from a variety of disciplines and applications. Data visualization is the interactive visual exploration of information using 2-D and 3-D graphics using techniques that highlight patterns and relationships. Data analysis incorporates data management, data transformations, stati...

2016
Bruce A. Maxwell

This course prepares students to apply computational approaches to data analysis and visualization to real information from a variety of disciplines and applications. Data visualization is the interactive visual exploration of information using 2-D and 3-D graphics using techniques that highlight patterns and relationships. Data analysis incorporates data management, data transformations, stati...

2007
Effat SOURI Abbas KEBRIAEE

Orlistat (Xenical) (Fig. 1), a highly lipophilic tetrahydro derivative of lipstatin, is an inhibitor of gastric and pancreatic lipases required for the hydrolysis of dietary fat (triacylglycerols) in the gastrointestinal tract into free fatty acids and monoacylglycerols. A major contributing factor to the development and maintenance of obesity is excessive intake of dietary triglycerides. Inhib...

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