نتایج جستجو برای: لایه واسط mbf

تعداد نتایج: 24566  

2005
Gianmario Sambuceti Danilo Neglia Mario Marzilli Piero Salvadori Antonio L'Abbate Oberdan Parodi

Background Recent evidence suggests that, in coronary artery disease (CAD), myocardial blood flow (MBF) regulation is abnormal in regions supplied by apparently normal coronary arteries. However, the relation between this alteration and MBF response to increasing metabolic demand has not been fully elucidated. Methods and Results MBF was assessed at baseline, during atrial pacing tachycardia, a...

Journal: :EMBO reports 2011
Blanca Gómez-Escoda Tsvetomira Ivanova Isabel A Calvo Isabel Alves-Rodrigues Elena Hidalgo José Ayté

When DNA replication is challenged cells activate a DNA synthesis checkpoint, blocking cell cycle progression until they are able to overcome the replication defects. In fission yeast, Cds1 is the effector kinase of this checkpoint, inhibiting M-phase entry, stabilizing stalled replication forks and triggering transcriptional activation of S-phase genes. The molecular basis of this last effect ...

Journal: :Circulation 1999
M Bøttcher H E Botker H Sonne T T Nielsen J Czernin

BACKGROUND Impaired vasodilatation capacity in patients with angina pectoris and a normal coronary arteriogram (syndrome X [SX]) has been reported. Most studies report on the response in epicardial vessels. This does not necessarily reflect compromised myocardial microcirculation. Lack of the NO precursor L-arginine has been suggested as a possible cause. METHODS AND RESULTS Myocardial blood ...

2011
Ilse A. Vermeltfoort Pieter G. Raijmakers Mark Lubberink Tjeerd Germans Albert C. van Rossum Adriaan A. Lammertsma Paul Knaapen

BACKGROUND Positron emission tomography (PET) enables robust and reproducible measurements of myocardial blood flow (MBF). However, the relatively limited resolution of PET till recently prohibited distinction between the subendocardial and the subepicardial layers in non-hypertrophied myocardium. Recent developments in hard- and software, however, have enabled to identify a transmural gradient...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012
Piotr J Slomka Erick Alexanderson Rodrigo Jácome Moises Jiménez Edgar Romero Aloha Meave Ludovic Le Meunier Magnus Dalhbom Daniel S Berman Guido Germano Heinrich Schelbert

UNLABELLED Several models for the quantitative analysis of myocardial blood flow (MBF) at stress and rest and myocardial flow reserve (MFR) with (13)N-ammonia myocardial perfusion PET have been implemented for clinical use. We aimed to compare quantitative results obtained from 3 software tools (QPET, syngo MBF, and PMOD), which perform PET MBF quantification with either a 2-compartment model (...

Journal: :European heart journal cardiovascular Imaging 2013
Hoshang Farhad Vincent Dunet Kim Bachelard Gilles Allenbach Philipp A Kaufmann John O Prior

AIMS We studied the respective added value of the quantitative myocardial blood flow (MBF) and the myocardial flow reserve (MFR) as assessed with (82)Rb positron emission tomography (PET)/CT in predicting major adverse cardiovascular events (MACEs) in patients with suspected myocardial ischaemia. METHODS AND RESULTS Myocardial perfusion images were analysed semi-quantitatively (SDS, summed di...

Journal: :Circulation 1994
S D Rosen N G Uren J C Kaski D Tousoulis G J Davies P G Camici

BACKGROUND It remains unclear whether myocardial ischemia due to coronary microvascular dysfunction is the cause of chest pain in syndrome X (chest pain, ischemic-like stress ECG despite angiographically normal coronary arteries). To assess the function of the coronary microcirculation and its relation to pain perception, we measured myocardial blood flow (MBF) and coronary vasodilator reserve ...

Journal: :Journal of applied physiology 2010
Helmut Habazettl Dimitris Athanasopoulos Wolfgang M Kuebler Harrieth Wagner Charis Roussos Peter D Wagner Juergen Ungruhe Spyros Zakynthinos Ioannis Vogiatzis

Near-infrared spectroscopy (NIRS) with the tracer indocyanine green (ICG) may be used for measuring muscle blood flow (MBF) during exercise, if arterial ICG concentration is measured simultaneously. Although pulse dye densitometry allows for noninvasive measurement of arterial dye concentration, this technique is sensitive to motion and may not be applicable during exercise. The aim of this stu...

Journal: :American journal of physiology. Heart and circulatory physiology 2008
Paul Knaapen Tjeerd Germans Paolo G Camici Ornella E Rimoldi Folkert J ten Cate Jurrien M ten Berg Pieter A Dijkmans Ronald Boellaard Willem G van Dockum Marco J W Götte Jos W R Twisk Albert C van Rossum Adriaan A Lammertsma Frans C Visser

Impaired hyperemic myocardial blood flow (MBF) in hypertrophic cardiomyopathy (HCM), despite normal epicardial coronary arteries, results in microvascular dysfunction. The aim of the present study was to determine the relative contribution of extravascular compressive forces to microvascular dysfunction in HCM. Eighteen patients with symptomatic HCM and normal coronary arteries and 10 age-match...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید