Cultivation of common hop (Humulus lupulus L.) has increased dramatically during the past decade, with primary growth occurring in Pacific Northwest United States. A major limitation to production is powdery mildew [caused by Podosphaera macularis (Wallr.) Braun & Takam]. To date, a comprehensive evaluation wild germplasm resources for resistance yet be conducted. Herein, we report first extens...

To study the anticoccidial and antioxidant effects of garlic powder (GP) and total sulfur amino acid (TSAA) on growth performance, faecal oocyst output, oxidative stress indicators and antioxidant status markers in broiler chickens, a 2 × 2 × 2 splitplot-factorial arrangement of treatments was used. A total of 480-day-old male broiler chickens were equally assigned to two plots. Two hundred for...

Insertion of the lymphocytic choriomeningitis virus (LCMV) precursor glycoprotein C (GP-C) into the membrane of the endoplasmic reticulum is mediated by an unusual signal peptide (SP(GP-C)). It is comprised of 58 amino acid residues and contains an extended hydrophilic N-terminal region, two hydrophobic regions, and a short C-terminal region. After cleavage by signal peptidase, SP(GP-C) accumul...

introduction: the aim of this study was to evaluate the retreatability of root canals obturated with gutta-percha (gp) and three different endodontic sealers [iroot sp (bioceramic sealer), mta fillapex (mta-based sealer) and ah-26 (epoxy resin-based sealer)] using the protaper universal retreatment (ptr) system. methods and materials: forty extracted single-rooted human teeth were prepared with...

Genetic Programming in Hardware This thesis describes a hardware implementation of a complete Genetic Programming (GP) system using a Field Programmable Gate Array, which is shown to speed-up GP by over 400 times when compared with a software implementation of the same algorithm. The hardware implements the creation of the initial population, breeding operators, parallel fitness evaluations and...

P-glycoprotein (P-gp) affects the transport of many drugs; including puerarin and vincristine. Our previous study demonstrated that imperatorin increased the intestinal absorption of puerarin and vincristine by inhibiting P-gp-mediated drug efflux. However; the underlying mechanism was not known. The present study investigated the mechanism by which imperatorin promotes P-gp-mediated drug trans...

UNLABELLED Homology modeling and structural analysis of human P-glycoprotein (hP-gp) were performed with a software package the Molecular Operating Environment (MOE). A mouse P-gp (mP-gp; PDB code: 3G5U) was selected as a template for the 3D structure modeling of hP-gp. The modeled hP-gp showed significant 3D similarities at the drug biding site (DBS) to the mP-gp structure. The contact energy ...

In Parkinsonism, subthalamic nucleus (STN) neurons and two types of external globus pallidus (GP) neuron inappropriately synchronise their firing in time with slow (∼1 Hz) or beta (13-30 Hz) oscillations in cortex. We recorded the activities of STN, Type-I GP (GP-TI) and Type-A GP (GP-TA) neurons in anaesthetised Parkinsonian rats during such oscillations to constrain a series of computational ...