Smoking and alcohol consumption are major risk factors for the development of esophageal squamous cell carcinoma (ESCC). Recent studies have demonstrated that smoking and alcohol consumption may be associated with altered DNA methylation in human cancer development. The aim of the present study was to evaluate methylation-modulated protein expression of tumor-related genes (TRGs) in the early s...

Enterprise social networks (ESN) have revolutionized collaboration between professional organizations. By means of an ESN, conventional mobility constraints, complex procedures for services exchange and the lack of flexibility and communication are no longer concerns. In this thesis we have worked on the project OpenPaaS ESN. Mainly we focused on the management of the access control, which led ...

In this paper we analyze an echo state neural network (ESN) in the presence of uncorrelated additive and multiplicative white Gaussian noise. Here consider case where artificial neurons have a linear activation function with different slope coefficients. We influence input signal, memory connection matrices on accumulation found that general view variance signal-to-noise ratio ESN output signal...

Abstract As a recurrent neural network, ESN has attracted wide attention because of its simple training process and unique reservoir structure, been applied to time series prediction other fields. However, also some shortcomings, such as the optimization collinearity. Many researchers try optimize structure performance deep by constructing ESN. with increase number network layers, problem low c...

The Web of Things (WoT) plays an important role in the representation of the objects connected to the Internet of Things in a more transparent and effective way. Thus, it enables seamless and ubiquitous web communication between users and the smart things. Considering the importance of WoT, we propose a WoT-based emerging sensor network (WoT-ESN), which collects data from sensors, routes sensor...

With the rapid development of wireless communication technology, the wireless spectrum resources are dwindling. Cognitive radio (CR) is the key technology to solve this problem. In view of the echo state network advantages compared to traditional recursive neural network, we construct the new neural network, echo state network based on leaky integrate and fire neurons (LIF_ESN), and prove that ...

The neural crest and neurogenic placodes are thought to be a vertebrate innovation that gives rise tomuch of the peripheral nervous system (PNS). Despite their importance for understanding chordate evolution and vertebrate origins, little is known about the evolutionary origin of these structures. Here, we investigated the mechanisms underlying the development of ascidian trunk epidermal sensor...

Immune activation has been suggested to increase susceptibility to human immunodeficiency virus type 1 (HIV-1) transmission, while at the same time it could be deemed essential for mounting an effective antiviral immune response. In this study, we compared levels of T cell activation between exposed seronegative (ESN) partners in HIV-1 discordant couples and HIV-unexposed control subjects in Da...