BACKGROUND Several studies have investigated plasma androgen levels in women with recurrent miscarriage (RM) with conflicting results on whether an association between hyperandrogenaemia and RM exists. However, none of these studies included sensitive androgen measurements using a large data set. We therefore investigated the free androgen index (FAI) in a large number of women with RM in order...

OBJECTIVE The objective of our study was to determine reference intervals and biologic variation for testosterone (T), free testosterone (fT), and free androgen index (FAI) in women with accurate methods and to test the discriminative value of these parameters in a polycystic ovary syndrome (PCOS)-population. METHODS Serum was obtained daily during a normal menstrual cycle from 25 healthy wom...

Femoroacetabular impingement (FAI) is an increasingly recognized condition, which is believed to contribute to degenerative changes of the hip. This correlation has led to a great deal of interested in diagnosis and treatment of FAI. FAI can be divided into two groups: cam and pincer type impingement. FAI can lead to chondral and labral pathologies, that if left untreated, can progress rapidly ...

BACKGROUND Symptomatic femoroacetabular impingement (FAI) is currently corrected by surgery. However, it is possible that nonsurgical treatment could resolve symptomatic FAI in some patients; thus, uncertainty about the necessity of surgical treatment exists. The current equipoise concerning FAI treatment presents an opportunity to conduct a randomized controlled trial (RCT) of surgical and non...

IMPORTANCE Elevated intraocular pressure (IOP) is a well-known adverse event associated with the fluocinolone acetonide implant (FAI), but no data are available regarding factors associated with increased risk of IOP elevation in patients treated with the FAI. OBJECTIVE To report risk factors that may predispose patients to elevated IOP after treatment with the FAI. DESIGN, SETTING, AND PAR...

Objectives: Femoroacetabular impingement (FAI) is considered a leading cause of early hip OA, but initial molecular mechanisms that lead FAI patients to OA progression remains be elucidated. Recent articles revealed epigenetic changes are associated with progression, specifically, DNA methyltransferase 3B (DNMT3B) plays critical role on cartilage homeostasis by attenuating catabolic gene expres...

results – “female gender (r = -.469, P < .001) and impaired balance (r = .495, P < .001).” Foot and ankle variables – “No significant gender differences (P <.05) were observed for age,” Variables associated with ankle instability – “Factors significantly associated with right FAI included female gender (r = -.469, P < .001),” “Factors associated with left FAI included female gender (r = .396, P...