We have used two murine monoclonal antibodies, each directed against one component of the human platelet membrane glycoprotein (GP) IIb-IIIa complex, to examine further the molecular requirements for fibrinogen binding to the platelet surface and subsequent platelet-platelet cohesion (aggregation). Although neither AP3, which is directed against GPIIIa, nor Tab, which is specific for GPIIb, wer...

The Indo-pacific araneid genus Anepsion, with A. rhomboides (L. Koch, 1867) as the type species, was erected by Strand in 1929. He proposed the name Anepsion as a replacement name for Anepsia L. Koch, 1871, preoccupied by Anepsia Gistl, 1848, a dipteran genus (OBIS Australia, 2015). The genus was revised by Chrysanthus (1961, 1969) and currently has 16 described species and 1 subspecies (World ...

THE student of geology in the course of his training usually passes through three stages of achievement: A first in which he learns to identify the materials with which he works; a second in which he learns to recognize the distribution of these materials in space; and a third in which, from this distribution, he interprets the geologic history of the area of the assemblage of materials. Paraph...

Soman, a powerful inhibitor of acetylcholinesterase, causes an array of toxic effects in the central nervous system including convulsions, learning and memory impairments, and, ultimately, death. We report on the protection afforded by postexposure antidotal treatments, combined with pyridostigmine (0.1 mg/kg) pretreatment, against these consequences associated with soman poisoning. Scopolamine...

Reduction of cross talk noise is an important characteristics clean signal quality for high-speed channel analysis. In this paper, tab added strip line modelled to improve distortion in digital circuits. A comprehensive analysis the proposed design done across frequency domain and time domain. 6dB improvement FEXT observed during 3mV eye height

The PARCTAB is a personal digital assistant (PDA) that communicates via infrared (IR) data-packets to a network of IR transceivers. The infrared network is designed for in-buildinguse, where each room becomes a communication cell. In contrast to the approach used by other PDAs, most PARCTAB applications run on remote hosts and therefore depend on reliable communication through the IR network. T...

Overexpression of the c-erbB-2 protein (gp185c-erbB-2) is correlated with a tumorigenic phenotype and may contribute to disease progression. We have reported previously on an anti-gp185c-erbB-2 antibody, TAb 250, that inhibits in vitro and in vivo growth of breast and ovarian cell lines that overexpress the protein and enhances the inhibitory activity of cisplatin (CDDP). To assess whether CDDP...

The monoclonal antibodies Tab and AP3 are directed, respectively, against GPllb and GPllla, the subunits of the platelet fibrinogen receptor. When added together to platelets, these antibodies prevent adenosine diphosphate (ADPI-induced platelet aggregation, despite normal fibrinogen binding (Newman et al. Blood 69:668, 1987). To explore the cellular requirements of aggregation after fibrinogen...