Pulp repair is a complex process whose mechanisms are not yet fully understood. The first immune cells to reach the damaged pulp are neutrophils that play an important role in releasing cytokines and in phagocytosis. The objective of this study was to analyze the effect of different pulp-capping materials on the secretion of interleukin-1 beta (IL-1β) and interleukin-8 (IL-8) by migrating human...

Xylan extracts from southern US hardwood were used for the adsorption of both hardwood and softwood pulp. Pulp beatability and physical strength properties were determined and compared with those of the conventional Kraft pulp and pre-extracted modified Kraft pulp. The results indicated that hemicelluloses adsorption greatly improved pulp beatability. Compared to conventional Kraft pulp, a sign...

OBJECTIVES The purpose of this study was to assess the ability of two new calcium silicate-based pulp-capping materials (Biodentine and BioAggregate) to induce healing in a rat pulp injury model and to compare them with mineral trioxide aggregate (MTA). MATERIALS AND METHODS Eighteen rats were anesthetized, cavities were prepared and the pulp was capped with either of ProRoot MTA, Biodentine,...

Pulp capping and pulpotomy procedures were performed on 15 male mongrel dogs. Three materials were used: calcium hydroxide, acid-etched dentin bonding, and mineral trioxide aggregate. Six of the animals were killed at 50 days and nine were killed at 150 days. Samples from 11 dogs were used for histological evaluation, and the remaining dog samples were used for scanning electron microscopy eval...

This study evaluated the histological pulp responses of four different adhesive resin systems placed directly on exposed pulp tissue. Gap formation between the respective resin and cavity walls was observed and correlated to the pulpal response. Occlusal cavity preparations creating mechanical pulp exposures were prepared in molars of wistar rats. Preparations were filled using one of the follo...

AIM To determine which methods of primary pulp therapy are currently being taught in European dental schools. METHODS An online survey tool was employed to send questionnaires to paediatric dentistry departments of 202 European dental schools. Email addresses were obtained from the European Academy of Paediatric Dentistry and questionnaires were sent to one member of each department in Decemb...

BACKGROUND This study examined the effects of addition of 10% and 25% by weight calcium hydroxide on the physicochemical properties of Portland cement associated with 20% bismuth oxide in order to develop a new pulp capping material. MATERIAL AND METHODS The solubility, pH value, setting time, compressive strength, and push out bond strength of modified Portland were evaluated and compared to...

We herein describe a novel procedure for dentin regeneration that mimics the biological processes of tooth development in nature. The canonical Wnt signaling pathway is an important regulator of the Dentin sialophosphoprotein (Dspp) expression. Our approach mimics the biological processes underlying tooth development in nature and focuses on the activation of canonical Wnt signaling to trigger ...

BACKGROUND AND OBJECTIVE A previous study [Moritz et al., Z Stomatol 1996; 93:451-454] had shown that favourable results in direct pulp capping could be achieved using a continuous wave CO2 laser in addition to the conventional calcium hydroxide dressing technique. In this study, these results are compared to those achieved using a CO2 laser working in superpulsed mode. STUDY DESIGN/MATERIALS...

The antimicrobial activity of visible light cure (VLC) calcium hydroxide pulp capping products was compared to self-cure products by an in vitro microbial assay. Individual microbial samples were collected from six deep carious lesions, sonicated, and plated onto duplicate T-soy blood agar. Uniform discs of each capping compound were pressed slightly below the surface of the agar and allowed to...