OBJECTIVES Prognostic factors for progression of benign adrenocortical adenomas (AI) remain poorly known. We assessed the usefulness of (131)I-6-beta-iodomethylnorcholesterol scintigraphy (IMS) to predict the occurrence of adrenal hyperfunction or mass enlargement. DESIGN Fifty-one consecutive inpatients with unilateral AI and normal 24-h urinary free cortisol (UFC) were enrolled in a multice...

Cushing’s disease due to adrenocorticotropin (ACTH)-secreting macroadenomas is rare. The aim of this study was to evaluate the clinical characteristics and biochemical assessment of patients with corticotroph macroadenomas,and the early and late outcomes of transsphenoidal surgery as the first surgical approach during a long-term follow-up. We performed a retrospective review of 20 patients wit...

Purpose: To evaluate models of gastric material collection from Wistar rats with and without using proton pump inhibitors(PPIs). Methods: Twenty-four rats underwent intraperitoneal omeprazol treatment, and other 12 received similar treatment with 0.9% saline. All animals underwent collection of gastric material samples, after stomach removal, by either biopsies, or aspirates, or swabs. Samples ...

Cabergoline is a long-acting dopamine receptor agonist used for treatment of patients with uncured Cushing's disease (CD) and, as a first-line treatment, was used in only limited numbers of patients. This report presents two adolescent boys with CD who were treated with cabergoline. Two adolescent boys with clinical and laboratory findings of CD are presented. No pituitary adenoma was detected ...

OBJECTIVE Transsphenoidal surgery (TSS) is the treatment of choice for Cushing's disease (CD). However, the best treatment option when hypercortisolism persists or recurs remains unknown. The aim of this study was to analyze the short and long-term outcome of repeat TSS in this situation and to search for response predictors. PATIENTS AND METHODS Data from 26 patients with persistent (n=11) o...

As a consequence of the exponential growth electric vehicle (EV) market, DC fast-charging infrastructure is being rapidly deployed all around world. Ultra-fast charging (UFC) stations are starting to pose serious challenges power system operation, mostly due their high peak demand and unregulated discontinuous operation. To address these issues, local energy storage can be installed, ensuring s...

The growing visibility of male Asian Ultimate Fighting Championship (UFC) fighters and the cultural affinity between martial arts Asianness call for reassessment dominant racial gender stereotypes. This study examines online UFC fans’ discursive formulation four scripts surrounding masculinities mixed (MMA) fighting – othering script, inferior artist script hypermasculine which contradict each ...

La faible compétitivité des produits locaux face à ceux importés est un handicap l’essor de la filière laitière locale et pourrait s’expliquer par insuffisances dans l’application règles d’hygiène. L’objectif ce travail était suivre in situ 5M les unités transformation afin contribuer maîtrise qualité hygiénique laitiers locaux. L’étude a été conduite juin 2021 janvier 2022 au sein trente (30) ...

OBJECTIVE To compare salivary, plasma and urinary free cortisol (UFC) measurements in patients with anorexia nervosa, in whom an overdrive of the hypothalamic-pituitary-adrenal (HPA) axis is well established but information on salivary cortisol is lacking, in viscerally obese patients in whom subtle abnormalities of cortisol secretion and metabolism are postulated, and in normal-weight healthy ...