نتایج جستجو برای: خودرو پژو 206

تعداد نتایج: 13114  

Journal: :Oncology reports 2015
Xiao-Wei Wang Xue-Qin Xi Jian Wu Yi-Yuan Wan Hong-Xia Hui Xiu-Feng Cao

Colorectal cancer (CRC) is the most common cancer diagnosed worldwide, and the development of metastases is a major cause of mortality. Accumulating evidence suggests that microRNAs are important in carcinogenesis by affecting the expression of genes that regulate cancer progression. A number of studies have shown that miR-206 is frequently downregulated in many human malignancies, including CR...

Journal: :Environmental pollution 2011
Guo-Xin Sun Xin-Jun Wang Qin-Hong Hu

Lead isotopes and heavy metal concentrations were measured in two sediment cores sampled in estuaries of Xiangjiang and Lishui Rivers in Hunan province, China. The presence of anthropogenic contribution was observed in both sediments, especially in Xiangjiang sediment. In the Xiangjiang sediment, the lower (206)Pb/(207)Pb and higher (208)Pb/(206)Pb ratio, than natural Pb isotope signature (1.19...

Journal: :International journal of clinical and experimental medicine 2015
Ya-Jun Zhang Feng Xu Yi-Jie Zhang Hong-Bing Li Ji-Chang Han Lei Li

BACKGROUND MicroRNAs (miRNAs) are a class of small non-coding RNAs that have been suggested to play an essential role in tumorigenesis. miR-206 functions as a tumor suppressor in several cancers. However, its role in non small cell lung cancer (NSCLC) remains unclear. METHODS Expression levels of miR-206 in NSCLC tissues and cell lines were determined by quantitative real-time PCR (qRT-PCR). ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علم و صنعت ایران 1380

هدف اصلی این پژوهش بررسی تاثیر فرهنگ کار بر تکنیک های بهبود بهره وری بکار گرفته شده در دو شرکت تولیدی-صنعتی بنام :الف، شرکت تولیدی آذین که در زمینه تولید تجهیزات و تزئینات داخلی خودروهای پیکان ، پژو و پراید فعالیت می کند. ب، شرکت شتاب که در زمینه تولید قطعات موتوری خودروی پیکان و پژو 405 فعالیت می کند .

2016
Kai Yin Wenjin Yin Yaohui Wang Liheng Zhou Yu Liu Gong Yang Jianhua Wang Jinsong Lu

BACKGROUND Previous reports have shown a mutual negative feedback loop between microRNA (miR)-206 and estrogen receptor (ER) expression. Furthermore, decreased miR-206 expression in breast cancer (BC) is associated with the advanced clinical stage and lymph node metastasis. However, its role and the mechanism underlying the migration and invasion of ER positive BC remain unclear. RESULTS In t...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Hiroyuki Inose Hiroki Ochi Ayako Kimura Koji Fujita Ren Xu Shingo Sato Makiko Iwasaki Satoko Sunamura Yasuhiro Takeuchi Seiji Fukumoto Kuniaki Saito Takashi Nakamura Haruhiko Siomi Hiroshi Ito Yoshiyasu Arai Ken-ichi Shinomiya Shu Takeda

Growing evidence shows that microRNAs (miRNAs) regulate various developmental and homeostatic events in vertebrates and invertebrates. Osteoblast differentiation is a key step in proper skeletal development and acquisition of bone mass; however, the physiological role of non-coding small RNAs, especially miRNAs, in osteoblast differentiation remains elusive. Here, through comprehensive analysis...

Journal: :Science 2009
Andrew H Williams Gregorio Valdez Viviana Moresi Xiaoxia Qi John McAnally Jeffrey L Elliott Rhonda Bassel-Duby Joshua R Sanes Eric N Olson

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of motor neurons, denervation of target muscles, muscle atrophy, and paralysis. Understanding ALS pathogenesis may require a fuller understanding of the bidirectional signaling between motor neurons and skeletal muscle fibers at neuromuscular synapses. Here, we show that a key regulator of this signaling is...

2009
Guisheng Song Li Wang

MicroRNAs play a critical role in many essential cellular functions in the mammalian species. However, limited information is available regarding the regulation of miRNAs gene transcription. Microarray profiling and real-time PCR analysis revealed a marked down-regulation of miR-206 in nuclear receptor SHP(-/-) mice. To understand the regulatory function of SHP with regard to miR-206 gene expre...

2015
Ankur Sharan Hairong Zhu Hua Xie Hongxing Li Junwei Tang Weibing Tang Hongwei Zhang Yankai Xia

Hirschsprung disease (HSCR) is a well-known congenital digestive disease that originates due to the developmental disorder of neural crest cells. MiR-206 is kown to have a relationship with digestive malfunctions. Therefore, we investigated whether or not miR-206 was involved in the pathogenesis of HSCR. qRT-PCR and Western blot assays were used to detect the expression levels of miRNA and mRNA...

2015
XUE YANG CHUANBAO ZHANG TIANZHU GUO YING FENG QINGYANG LIU YAN CHEN QUANGENG ZHANG

MicroRNAs are short single‑stranded non‑coding RNA molecules that function as regulators of tumor progression, including regulation of glioblastoma multiforme, which is a World Health Organization grade Ⅳ glioma. Based on the results of a microRNA microarray, which included 198 patients with glioma from the Chinese Glioma Genome Atlas data set, it was observed that microRNA‑206 (miR‑206) was do...

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