A bacteriocin produced by Bacillus megaterium ATCC 19213 was identified, purified, and compared with megacin A from B. megaterium 216. The ATCC 19213 bacteriocin was inducible with mitomycin C and showed phospholipase A activity. Both megacin A-216 and megacin A-19213 contained two dissimilar polypeptide subunits. Megacin A-216 contains a 30,000-dalton alpha subunit and a 15,000-dalton beta sub...

dominik strzelecki1, Olga Kałużyńska2, Jolanta Rabe-Jabłońska1: 1 Department of Affective and Psychotic Disorders, University of Łódź, 8/10 czechosłowacka Str., 92-216 Łódź, Poland. 2 central clinical Hospital, 8/10 czechosłowacka Str., 92-216 Łódź, Poland. correspondence address: Dominik Strzelecki, Department of Affective and Psychotic Disorders, University of Łódź, 8/10 czechosłowacka Str., ...

AIMS Apolipoprotein A-1 (ApoA-1), based on epidemiology, is inversely associated with cardiovascular (CV) events. Human carriers of the ApoA-1 Milano variant have a reduced incidence of CV disease. Regression of atherosclerotic plaque burden was previously observed on intravascular ultrasound (IVUS) with ETC-216, a predecessor of MDCO-216. MDCO-216, a complex of dimeric ApoA-1 Milano and 1-palm...

PURPOSE Lapatinib is a candidate drug for treatment of trastuzumab-resistant, human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC). Unfortunately, lapatinib resistance renders this drug ineffective. The present study investigated the implication of forkhead box O1 (FOXO1) signaling in the acquired lapatinib resistance in HER2-positive GC cells. MATERIALS AND METHODS La...

MDCO-216 is a complex of dimeric ApoA-IMilano and palmitoyl oleoyl phosphatidylcholine (POPC), previously shown to reduce atherosclerotic plaque burden. Here we studied the effect of incubation of human plasma or serum with MDCO-216 on cholesterol efflux capacity from J774 cells, on prebeta-1 high density lipoprotein (prebeta-1 HDL) and on HDL size assessed by proton nuclear magnetic resonance ...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Kurzeja M, Pawlik K, Sienicka A, Olszewska Rudnicka L. Infantile hemangioma. Dermatology Review/Przegląd Dermatologiczny. 2022;109(3):204-216. doi:10.5114/dr.2022.120178. APA Kurzeja, M., Pawlik, K., Sienicka, A., Olszewska, & Rudnicka, (2022). Dermatologiczny, 109(3), 204-216. https://doi.org/10.5114/dr.2022.1201...