نتایج جستجو برای: حداکثر مدت زمان آواسازی mpt
تعداد نتایج: 158559 فیلتر نتایج به سال:
A general comparison is made between the multinomial processing tree (MPT) approach and a strengthbased approach for modeling recognition memory measurement. Strength models include the signaldetection model and the dual-process model. Existing MPT models for recognition memory and a new generic MPT model, called the Multistate (MS) model, are contrasted with the strength models. Although the R...
Mitochondrial uptake of calcium in excitotoxicity is associated with subsequent increase in reactive oxygen species (ROS) generation and delayed cellular calcium deregulation in ischemic and neurodegenerative insults. The mechanisms linking mitochondrial calcium uptake and ROS production remain unknown but activation of the mitochondrial permeability transition (mPT) may be one such mechanism. ...
In this double-blind, placebo-controlled study, 363 patients with untreated multiple myeloma were randomized to receive either melphalan-prednisone and thalidomide (MPT) or melphalan-prednisone and placebo (MP). The dose of melphalan was 0.25 mg/kg and prednisone was 100 mg given daily for 4 days every 6 weeks until plateau phase. The dose of thalidomide/placebo was escalated to 400 mg daily un...
Mitochondrial permeability transition (MPT) is thought to determine cell death under oxidative stress. However, MPT inhibitors only partially suppress oxidative stress-induced cell death. Here, we demonstrate that cells in which MPT is inhibited undergo cell death under oxidative stress. When C6 cells were exposed to 250 μM t-butyl hydroperoxide (t-BuOOH), the loss of a membrane potential-sensi...
The objective of the present study was to validate the presence and explore the characteristics of mitochondrial permeability transition (mPT) in isolated mitochondria from human heart tissue in order to investigate if previous findings in animal models of cardiac disorders are translatable to human disease. Mitochondria were rapidly isolated from fresh atrial tissue samples obtained from 14 pa...
در دیدگاه های اولیه برای تولید محصولات از روش های سنتی استفاده می کردند که بر شاخص هزینه های عملیاتی تمرکز داشتند و بعد از آن روش تولید به موقع که به از بین بردن ضایعات توجه خاصی داشت مورد استفاده قرار گرفت. با توجه به مطرح شدن رقابت ، مدیران به این نتیجه رسیدند که دو روش موجود بیشتر برای تولید محصولاتی با تنوع کم مناسب هستند. بنابراین روش تئوری محدودیت ها از طریق شناسایی و حذف گلوگاه به عنوان ...
به منظور بررسی اثر مدت زمان و دمای پیشتیمار رطوبتی بر شاخصهای جوانهزنی و بنیه گیاهچه شاهی در بسترهای مختلف، آزمایشی در سال 1393 در آزمایشگاه گیاهشناسی مرکز آموزش کشاورزی دانشگاه جامع علمی کاربردی استان گیلان به صورت فاکتوریل در قالب طرح بلوکهای کامل تصادفی با سه تکرار اجرا شد. فاکتورهای این تحقیق شامل دو نوع بستر جوانهزنی (کاغذ و ماسه)، مدت زمان پیشتیمار رطوبتی در سه سطح (بلافاصله، 6 ساع...
This retrospective study was conducted to confirm the relationship between pre- and postpartum metabolic parameters and postpartum reproductive performance and to clarify seasonal characteristics of the metabolic parameters by using our metabolic profile test (MPT) database of Japanese Black breeding herds. In evaluation 1, MPT databases of blood samples from multiparous cows collected prepartu...
The membrane permeability transition (MPT) of mitochondria plays an important role in the mechanism of apoptotic cell death in various cells. Classic type MPT is induced by Ca(2+) in the presence of inorganic phosphate and respiratory substrate, and is characterized by various events including generation of reactive oxygen species (ROS), membrane depolarization, swelling, release of Ca(2+) and ...
The epidermal growth factor receptor (EGFR) is known to play a critical role in non-small cell lung cancer(NSCLC). Several EGFR tyrosine kinase inhibitors(TKIs), such as gefitinib, have been used as effective clinical therapies for patients with NSCLC. Unfortunately, acquired resistance to gefitinib commonly occurs after 6-12 months of treatment. The resistance is associated with the appearance...
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