n-3 Polyunsaturated fatty acids (n-3 PUFA) have been shown to reduce inflammation and proliferation of pulmonary artery smooth muscle cells under pathophysiological conditions. However, the anti-inflammatory effect of the newly synthesized docosapentaenoic acid monoacylglyceride (MAG-DPA) on key signaling pathways in pulmonary hypertension (PH) pathogenesis has yet to be assessed. The aim of th...

We present new R filtered CCD observations of 5 faint and moderately faint asteroids carried out between October, 1998 and January, 1999. The achieved accuracy is between 0.01–0.03 mag, depending mainly on the target brightness. The obtained sinodic periods and amplitudes: 683 Lanzia – 4. h6±0. 2, 0.13 mag; 725 Amanda – > 3. 0, ≥0.40 mag; 852 Wladilena – 4. h62±0. 01, 0.32 mag (December, 1998) ...

– 2 – We present distance determinations for two Local Group dwarf spheroidal galaxies, Carina and Fornax, based on the near-infrared magnitudes of the tip of the red giant branch (TRGB). For Carina we derive true distance moduli of 20.09 and 20.13 mag in the J and K bands, respectively, while for Fornax the same distance modulus of 20.84 mag was derived in both filters. The statistical errors ...

BACKGROUND Pulmonary artery vasoconstriction and vascular remodeling contribute to a sustained elevation of pulmonary vascular resistance and pressure in patients with pulmonary arterial hypertension (PH), an often fatal hemodynamic disease. The effect of docosahexaenoic acid monoacylglyceride (MAG-DHA) and the role of the 17 kDa protein kinase C-potentiated inhibitor protein (CPI-17) were dete...

The preparation and thorough characterization of a hybrid magnetic carrier system for the possible transport of activated platinum-based anticancer drugs, as demonstrated for cisplatin (cis-[Pt(NH3)2Cl2], CDDP), are described. The final functionalized mag/Au-LA-CDDP* system consists of maghemite/gold nanoparticles (mag/Au) coated by lipoic acid (HLA; LA stands for deprotonated form of lipoic ac...

We present the algebraic representation and basic algorithms of MultiAspect Graphs (MAGs), a structure capable of representing multilayer and time-varying networks while also having the property of being isomorphic to a directed graph. In particular, we show that, as a consequence of the properties associated with the MAG structure, a MAG can be represented in matrix form. Moreover, we also sho...

Monoacylglycerols (MAGs) are structural and bioactive metabolites critical for biological function. Development of facile tools for measuring MAG are essential to understand its role in different diseases and various pathways. A data-independent acquisition method, MS/MS(ALL), using electrospray ionization (ESI) coupled quadrupole time of flight mass spectrometry (MS), was utilized for the stru...

We have observed emission from the 492 GHz lines of C I toward six positions in the Ophiuchus molecular cloud complex for which accurate visual extinctions are available. We find that the column density of C I increases with Av to greater than 2 x 1017 em 2 at 100 mag, the column-averaged fractional abundance reaches a peak of about 2.2 x 10-s for Av in the range 4-11 mag and the column-average...

The morphological properties of galaxies between 21 mag < I < 25 mag in the Hubble Deep Field are investigated using a quantitative classification system based on measurements of the central concentration and asymmetry of galaxian light. The class distribution of objects in the Hubble Deep Field is strongly skewed towards highly asymmetric objects, relative to distributions from both the HST Me...