Over the past decades, the diagnostic methods and therapeutic tools for thyroid cancer (TC) have been greatly improved. In addition to the classical method of ingestion of radioactive iodine-131 (I131) and subsequent I123 and I124 positron emission tomography (PET) in therapy and examination, I124 PET-based 3-dimensional imaging, Ga68-labeled [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetra...

Four cationic ruthenium(II) complexes with the formula [Ru(eta(5)-C(5)H(5))(PPh(3))(2)](+), with L = 5-phenyl-1H-tetrazole (TzH) 1, imidazole (ImH) 2, benzo[1,2-b;4,3-b'] dithio-phen-2-carbonitrile (Bzt) 3, and [5-(2-thiophen-2-yl)-vinyl]-thiophene-2-carbonitrile] (Tvt) 4 were prepared and characterized in view to evaluate their potentialities as antitumor agents. Studies by Circular Dichroism ...

Aim: Chronic hepatitis B virus (HBV) infection can induce nephropathy and major HBV antigens (HBcAg, HBeAg, HBsAg) and immune complexes responsible for its pathogenesis. The purpose of our study was to assess the renal function of patients with HBV infection by means of technetium diethylenetriamine pentaacetic acid (Tc99m DTPA) scintigraphy, in order to detect any early renal dysfunction, whic...

Objective: The aim of this study is to assess brain perfusion SPECT as a diagnostic tool in detection of subclinical cognitive deficits in non-demented elderly people. METHODS: The tracer distribution was measured with Tc99m-HMPAO and SPECT in 37 elderly subjects; age range 60-84 yrs. Results: Patients were divided according to Mini-Mental State Examination (MMSE) into 3 groups: Group II with g...

Catalytic asymmetric hydrogenation of N-Boc-protected pyrroles proceeded with high enantioselectivity by using a ruthenium catalyst modified with a trans-chelating chiral bisphosphine PhTRAP. The ruthenium catalyst prepared from Ru(eta3-methallyl)2(cod) and (S,S)-(R,R)-PhTRAP in the presence of triethylamine was the most enantioselective for the asymmetric hydrogenation of methyl pyrrole-2-carb...

PURPOSE In previous work, the authors developed and demonstrated the concept of an image reconstruction procedure aimed to unify gated and dynamic nuclear cardiac imaging, which the authors have termed five-dimensional (5D) SPECT. Gated imaging permits the clinician to evaluate wall motion and, through the use of stress and rest scans, allows perfusion defects to be observed. Dynamic imaging de...