The combination of idiopathic pulmonary hemosiderosis (IPH) and celiac disease (CD) is rare. The clinical importance of this association is that a significant improvement can be obtained with gluten free diet not only in intestinal but also in pulmonary symptoms. A four and half-years old girl was admitted with complaints of cough, difficulty in breathing and paleness. She had intermittent epis...

A 22-year-old man with a history of repeated whole blood transfusions since the age of 7, was admitted to the hospital for dyspnea and blood-stained sputum. A complete blood cell count, a test for reticulin antibodies, an x-ray film of the chest, a transbronchial biopsy and a biopsy of the small bowel were performed and the results confirmed the diagnosis of IPH, associated with CD. The patient...

A Simultaneous Non-contrast Angiography and intraPlaque hemorrhage (SNAP) MR imaging technique was proposed to detect both luminal stenosis and hemorrhage in atherosclerosis patients in a single scan. 13 patients with diagnosed carotid atherosclerotic plaque were recruited after informed consent. All scans were performed on a 3T MR imaging system with SNAP, 2D time-offlight (TOF) and magnetizat...

Looking Beyond the Lumen Does Make All the Difference To the Editor: We read with interest the article by Takaya et al,1 and the accompanying editorial, further supporting the hypothesis that intraplaque hemorrhage (IPH) occupies a central role in the progression of atheroma and is commonly associated with symptom generation. A means by which IPH can be readily identified, noninvasively, will o...

RATIONALE The complex and multifactorial pathogenesis of pulmonary hypertension (PH) involves constriction, remodeling, and in situ thrombosis of pulmonary vessels. Both serotonin (5-HT) and Rho kinase signaling may contribute to these alterations. OBJECTIVES To investigate possible links between the 5-HT transporter (5-HTT) and RhoA/Rho kinase pathways, as well as their involvement in the pr...

OBJECTIVE To investigate the association between the pathological features of carotid plaque and ipsilateral symptoms of cerebral ischemia. MATERIALS AND METHODS We sought to identify clinical observational studies comparing the incidence of pathological features between symptomatic and asymptomatic carotid plaques in terms of ulceration, thrombosis and intraplaque hemorrhage (IPH), published...

Correlation Between Carotid Intraplaque Hemorrhage and Clinical Symptoms To the Editor: In the systematic review by Gao et al about the correlation between intraplaque hemorrhage (IPH) and neurological symptoms in patients with carotid disease,1 the authors analyzed findings from 31 observational studies in order to determine the role of IPH as a predictor of cerebral ischemic events, and demon...

Hemorrhage in Coronary Artery Disease Intraplaque hemorrhage (IPH) is a phenomenon observed in advanced atherosclerotic plaques. Paterson was the first to propose vasa vasorum as the source of IPH. Barger et al described an abundance of plaque microvessels found in diseased coronary arteries compared with healthy ones and proposed that plaque neovascularization plays an important role in the pa...

The study discusses the role of prosodic grouping in the Mandarin Relative Clause attachment disambiguation. The grouping effect is explored under the Implicit Prosody Hypothesis (IPH) from four aspects of sentence processing experiments: default production, contrast production, online processing, as well as offline processing. It is found that (1) the length of RC greatly impacts ambiguity res...