نتایج جستجو برای: تست ایمز ames test
تعداد نتایج: 830583 فیلتر نتایج به سال:
Background and Objective: Nowadays, colors are widely used in various food industries, including sweets, confectionery, ice cream, beverages, and so on. Colors can have asthma-like complications, hyperactivity in children and cancers. Therefore, the aim of this study was to evaluate the direct mutagenic effect of several types of natural colors via Ames method. Materials and Methods: After pre...
Background: Hospitals discharge considerable amounts of chemicals in their wastewaters that may be genotoxic or present serious health hazards. The genotoxic potential of wastewater in a Lebanese University Hospital was evaluated using the SOS Chromotest and the Ames fluctuation test. Different concentrations were tested to determine the recommended dilution for each sample to decrease its geno...
OBJECTIVES Emodin is a bioactive anthraquinone that has diverse biological effects. It is also known as a biosynthetic precursor of hypericin. The purpose of this study was to assess mechanisms of potential genotoxic and antioxidant effects of emodin. We also investigated the potential genotoxic effect of photoactivated emodin. METHODS Potential genotoxicity was determined by the alkaline com...
Anemopsis californica has been used empirically to treat infectious diseases. However, there are no antimutagenic evaluation reports on this plant. The present study evaluated the antioxidant activity in relation to the mutagenic and antimutagenic activity properties of leaf (LME) and stem (SME) methanolic extracts of A. californica collected in the central Mexican state of Querétaro. Antioxida...
Studies have shown that Casearia sylvestris compounds protect DNA from damage both in vitro and in vivo. Complementarily, the aim of the present study was to assess the chemopreventive effect of casearin B (CASB) against DNA damage using the Ames test, the comet assay and the DCFDA antioxidant assay. The genotoxicity was assessed by the comet assay in HepG2 cells. CASB was genotoxic at concentr...
Background: Nowadays, cancer is one of the main causes of mortality in the world and many mutagens are the cause of death in millions of patients. Due to the side effects of anticancer drugs, scientists are in search of natural drugs with fewer side effects and more therapeutic efficacy. This study aims to, firstly, investigate the antimutgenic effects of different Aloe vera gel and latex extra...
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