We describe algorithms for polynomial factorization over the binary field F2, and their implementation. They allow polynomials of degree up to 250 000 to be factored in about one day of CPU time, distributing the work on two processors.

The ability for a host to recognize infection is critical for virus clearance and often begins with induction of inflammation. The PB1-F2 of pathogenic influenza A viruses (IAV) contributes to the pathophysiology of infection, although the mechanism for this is unclear. The NLRP3-inflammasome has been implicated in IAV pathogenesis, but whether IAV virulence proteins can be activators of the co...

The aim of the present study was to identify what influences the short half-life of the influenza A virus PB1-F2 protein and whether a prolonged half-life affects the properties of this molecule. We hypothesized that the short half-life of PB1-F2 could conceal the phenotype of the protein. Because proteasome degradation might be involved in PB1-F2 degradation, we focused on ubiquitination, a co...

Background This study aimed to assess the impact of perinatal high-fat (HF) diet in female Sprague-Dawley rats (F0) on glucose metabolism and islet function in their early life of second-generation of offspring (F2). Methods F0 rats were fed with a standard chow (SC) or HF diet for 8 weeks before mating, up to termination of lactation for their first-generation of offspring (F1-SC and F1-HF)....

Identification of place of articulation in the synthesized syllables /bi/, /di/, and /gi/ was examined in three groups of listeners: (a) normal hearers, (b) subjects with high-frequency sensorineural hearing loss, and (c) normally hearing subjects listening in noise. Stimuli with an appropriate second formant (F2) transition (moving-F2 stimuli) were compared with stimuli in which F2 was constan...