In the second part of this study, a systematic comparison was made between two ion fragmentation acquisition modes, namely data-independent (DIA) and DIA with mobility spectrometry (IMS) technology. These approaches were applied to analysis 192 doping agents in urine. Group I included 102 compounds such as stimulants, diuretics, narcotics, β2-agonists, while II contained 90 steroids, glucocorti...

A novel analysis of explosives via the coupling of an airline passenger personnel portal with a high-flow (HF), high-resolution (HR) ion mobility spectrometry (IMS) was shown for the first time. The HF-HR-IMS utilized a novel ion aperture grid design with a (63)Ni ionization source while operating at ambient pressure in the positive ion mode at 200 degrees C. The HF-HR-IMS response characterist...

AIMS The aim of this study was to isolate Escherichia coli O26, O103, O111 and O145 from 745 samples of bovine faeces using (i) immunomagnetic separation (IMS) beads coated with antibodies to lipopolysaccharide, and slide agglutination (SA) tests and (ii) PCR and DNA probes for the detection of the Verocytotoxin (VT) genes. METHODS AND RESULTS IMS-SA tests detected 132 isolates of presumptive...

Various indolylmaleimides (IMs) were synthesized, and their fluorescence (FL) and chemiluminescence (CL) were measured. The substitution at the 2-position of the indole ring and the 3- or 4-position of the maleimide moiety caused an obvious change in the FL and CL of the IMs. An almost on-off switching of the FL of the IMs was observed. The intramolecular charge transfer from the indole moiety ...

RAJAGOPAL, NISHA. Modeling and Performance Prediction of IP Multimedia Subsystem Networks. (Under the direction of Professor Michael Devetsikiotis). IP Multimedia Subsystem (IMS) is envisioned as the solution for the next generation multimedia rich communication. Based on an open IP infrastructure, IMS enables access independent convergence of data, speech, video and mobile network technologies...

Replication of flaviviruses (family Flaviviridae) occurs in specialized virus-induced membrane structures (IMS). The cellular composition of these IMS varies for different flaviviruses implying different organelle origins for IMS biogenesis. The role of flavivirus non-structural (NS) proteins for the alteration of IMS remains controversial. In this report, we demonstrate that West Nile virus st...

In order to understand whether conceptual obscurity is truly the reason for the slow uptake of IMS Learning Design (LD), we have initiated an investigation into teachers’ understanding of IMS LD outside of technological environments. Using paper representations (“snippets”) of IMS LD component and method elements at levels A and B, 21 higher education teachers from nine countries recreated a pr...

The IP Multimedia Subsystem (IMS) defined by the 3rd Generation Partnership Projects (3GPP) is a standardized architecture for the Next Generation Network. In this paper, we provide an insight into the presence service, one of the fundamental building blocks of the IMS. Our prototype-based study is unique of its kind and helps identifying the factors which limit the scalability of the current v...

We describe here a pathway for the import of proteins into the intermembrane space (IMS) of mitochondria. Substrates of this pathway are proteins with conserved cysteine motifs, which are critical for import. After passage through the TOM channel, these proteins are covalently trapped by Mia40 via disulfide bridges. Mia40 contains cysteine residues, which are oxidized by the sulfhydryl oxidase ...