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تعداد نتایج: 31104 فیلتر نتایج به سال:
PURPOSE We sought to compare the economic impact of treatment-related adverse events (AEs) in patients with metastatic breast cancer (mBC) using taxane- or capecitabine-based treatment regimens as either first- or second-line (FL or SL) therapy in the US. METHODS We used healthcare claims data from the Truven Health Analytics MarketScan® Commercial Databases to conduct a retrospective cohort ...
Since Rijndael was chosen as the Advanced Encryption Standard (AES), improving upon 7-round attacks on the 128-bit key variant (out of 10 rounds) or upon 8-round attacks on the 192/256-bit key variants (out of 12/14 rounds) has been one of the most difficult challenges in the cryptanalysis of block ciphers for more than a decade. In this paper, we present the novel technique of block cipher cry...
The purine analogues tenofovir and abacavir are precursors of potential substrates for the enzyme Inosine 5'-triphosphate pyrophosphohydrolase (ITPase). Here, we investigated the association of ITPase activity and ITPA genotype with the occurrence of adverse events (AEs) during combination antiretroviral therapy (cART) for human immunodeficiency virus (HIV) infection. In 393 adult HIV-seroposit...
This study aimed to analyse UK pharmacovigilance data to quantify adverse events (AEs) associated with the non-steroidal anti-inflammatory drug (NSAID) molecules found in veterinary medicines authorised for use in dogs and cats. It was hypothesised that the frequency of AEs would be lower when associated with cyclo-oxygenase-2 selective (coxib), compared to non-selective (non-coxib) NSAIDs. The...
BACKGROUND AND OBJECTIVES The relationship of contrast-induced nephropathy (CIN) to long-term adverse events (AEs) is controversial. Although an association with AEs has been previously reported, it is unclear whether CIN is causally related to these AEs. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We obtained long-term (> or =1 yr) follow-up on 294 patients who participated in a randomized...
OBJECTIVE To analyze the features of preventable adverse events (AEs) in hospitals inpatient in the State of Rio de Janeiro, in Brazil, in order to identify elements that serve as a substrate for priority actions aimed at improving patient safety. METHODS Analysis of data from a baseline retrospective cohort study to assess the incidence of AEs in a sample of records in three teaching hospita...
A system for morphing the softness and brightness of two sounds independently from their other perceptual or acoustic attributes was coded. The system is an extension of a previous one that morphed brightness only, that was based on the Spectral Modelling Synthesis additive/residual model. A Multidimensional Scaling analysis, of listener responses to paired comparisons of stimuli generated by t...
SCENIC is an EC-funded project aimed at developing a harmonized corpus of methodologies for environmentaware acoustic sensing and rendering. The project focusses on space-time acoustic processing solutions that do not just accommodate the environment in the modeling process but that make the environment help towards achieving the goal at hand. The solutions developed within this project cover a...
---------------------------------------------------------------------***--------------------------------------------------------------------Abstract The emerging need of the secure ciphers has lead to the designing and analysis of many lightweight block ciphers. In this respect, many lightweight block ciphers have been designed, of which is simple AES, one of the popular proposed secure block c...
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