OBJECTIVE to evaluate the prevalence and clinical significance of anti-chromatin antibodies (Abs) in juvenile rheumatoid arthritis (JRA). METHODS IgG anti-chromatin Abs were detected by an enzyme-linked immunosorbent assay (ELISA), in sera of 94 children with JRA (10 children with systemic, 38 with polyarticular and 46 with oligoarticular disease onset). As control group, 33 age- and-sex-matc...

Secretory immunoglobulin A (S-IgA) was investigated in human secretions for the presence of natural antibodies (Abs) acting as the first "immune barrier" to infection before induction or boosting of specific responses. These molecules could be the secretory counterpart of the natural Abs in serum that were previously shown by our laboratory to be polyreactive to autoantigens. Significant levels...

Neuropsychiatric systemic lupus erythematosus, which often entails cognitive disturbances and memory loss, has become a major complication for lupus patients. Previously, we developed a murine model of neuropsychiatric lupus based on Abs that cross-react with dsDNA and the NMDA receptor (NMDAR). We showed that these murine Abs impair cognition when they access the CNS through a breach in the bl...

Objetivo: Relatar a experiência de reorganização do acesso às unidades Atenção Básica à Saúde (ABS) no município Jaraguá Sul. Método: Foram utilizadas como estratégias mudança fluxo para avançado, incremento das consultas enfermagem e realização mutirões consulta médica melhoria diminuição da fila espera por na ABS. Resultados: A combinação conseguiu progressivamente diminuir ABS, sendo mais ev...

Objective: To assess a patient who developed Apical Ballooning Syndrome (ABS) Aim: To evaluate the potential factors leading to ABS Background: Apical Ballooning Syndrome is a cause of reversible cardiomyopathy that usually occurs in postmenopausal women. To date, no single cause of ABS has been identified; rather, ABS appears to be a consequence of multiple factors. Methods: This report evalua...

ABS methods are a large class of methods, based upon the Egervary rank reducing algebraic process, first introduced in 1984 by Abaffy, Broyden and Spedicato for solving linear algebraic systems, and later extended to nonlinear algebraic equations, to optimization problems and other fields; software based upon ABS methods is now under development. Current ABS literature consists of about 400 pap...

The Abstract Behavioral Specification (ABS) language facilitates to precisely model the behavior of highly configurable, distributed systems. Its basis is Core ABS which is a strongly typed, abstract, objectbased, concurrent, fully executable modeling language. Spatial variability of ABS models is represented by feature models, delta modules containing modifications of ABS models, product line ...

The role of natural idiotypic (Id-Abs) and anti-idiotypic (AId-Abs) autoantibodies against neuroantigens observed in different neurological disorders is not fully understood. In particular, limited experimental evidence has been provided concerning the qualitative and quantitative serological response after acute injuries of the central nervous system or during chronic mental diseases. In this ...