An assessment of levels of Insulin in cadaveric fluids, to estimate the postmortem interval (PMI) was carried out. To profile postmortem changes of Insulin, it was extracted at different intervals i.e. (0, 3, 6, 12, 24 h), from the heart of 22 human cadavers. The cases included were the subjects of accidental deaths without any prior history of disease and their exact time of death was known. I...

This paper presents a simple unsupervised learning algorithm for recognizing synonyms, based on statistical data acquired by querying a Web search engine. The algorithm, called PMI-IR, uses Pointwise Mutual Information (PMI) and Information Retrieval (IR) to measure the similarity of pairs of words. PMI-IR is empirically evaluated using 80 synonym test questions from the Test of English as a Fo...

The extant literature tends to frame mergers and acquisitions (M&As) and postmerger integration (PMI) as strategies and outcomes, but this framing often leaves their underlying processes underexplored. We address this gap by redirecting attention to the view that M&As are largely embedded in social and human practices. Our conceptual study identifies three generic M&A strategies—annex & assimil...

Establishing the time since death is critical in every death investigation, yet existing techniques are susceptible to a range of errors and biases. For example, forensic entomology is widely used to assess the postmortem interval (PMI), but errors can range from days to months. Microbes may provide a novel method for estimating PMI that avoids many of these limitations. Here we show that postm...

Duplications and triplications of the α-synuclein (SNCA) gene increase risk for PD, suggesting increased expression levels of the gene to be associated with increased PD risk. However, past SNCA expression studies in brain tissue report inconsistent results. We examined expression of the full-length SNCA transcript (140 amino acid protein isoform), as well as total SNCA mRNA levels in 165 front...

We report the case of a 64-year-old male with persistent atrial fibrillation (AF) terminated by ethanol infusion into vein of Marshall as add-on therapy. Three-dimensional automated complex fractionated atrial electrogram (CFAE) during AF revealed clustering of CFAE at perimitral isthmus (PMI) and its unipolar mapping showed rotor-like activation, which was suggested to be critical in the perpe...

Originality, a key aspect of creativity, is difficult to measure. We tested the relationship between originality and similarity in two semantic spaces: latent semantic analysis (LSA) and pointwise mutual information (PMI). Similarity in both spaces was negatively correlated with human judgments of originality of responses on a test of divergent thinking. PMI was correlated more strongly both wi...

The purchasing managers’ index (PMI) is a simple subjective survey about the state of the manufacturing sector of the national economy. It’s an early indicator of the nation’s economic strength with effects extending into federal monetary policy and the financial markets. It is a composite index comprising the weighted average of new orders, production, employment, supplier deliveries, and inve...

We previously reported that PMI-5011, an ethanolic extract of Artemisia dracunculus L., alleviates peripheral neuropathy in high fat diet-fed mice, a model of prediabetes and obesity developing oxidative stress and pro-inflammatory changes in the peripheral nervous system. This study evaluated PMI-5011 on established functional, structural, and biochemical changes associated with Type I diabeti...