نتایج جستجو برای: استعمال سیگارnucleolar organizer region nor
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OBJECTIVE This study was undertaken to determine whether the expressions of 3 proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein could differentiate spontaneous abortions from gestational trophoblastic diseases and also discriminate among gestational trophoblastic disease subgroups. STUDY DESIGN Twenty-tw...
Failure of one parent's chromosomes to organize nucleoli in an interspecific hybrid is an epigenetic phenomenon known as nucleolar dominance. Selective gene silencing on a scale of millions of bp is known to be involved, but the full extent to which nucleolus organizer region (NOR)-bearing chromosomes are inactivated beyond the NORs is unknown. Aided by genome sequence data for Arabidopsis thal...
We carried out a high-resolution ultrastructural analysis of the nucleolus in mouse P815 cells by combining specific DNA and RNA staining, anti-fibrillarin immunolabeling, contrast enhancement by energy filtering TEM and phosphorus mapping by ESI to visualize nucleic acids. We demonstrated that specifically contrasted DNA, fibrillarin and phosphorus overlap within the nucleolar dense fibrillar ...
Cells of the established cell lines of the rat kangaroo (Puotorous tridactylis), were laser microirradiated in order to study their nucleolar organizers. Microbeam irradiation of prophase and metaphase nucleolar organizer sites in both male (PTK 1) and female (PTK2) cells resulted in a reduction in the number of normal nucleoli formed following mitosis. Irradiation of the one nucleolar organize...
noggin is expressed in the Spemann organizer region of the Xenopus embryo and can promote dorsal cell fates within the mesoderm and neural development within the overlying ectoderm. Here, we show that noggin promotes ventral development in Drosophila, specifying ventral ectoderm and CNS in the absence of all endogenous ventral-specific zygotic gene expression. We utilize constitutively active f...
INTRODUCTION I N a previous paper (Lakshmi, 1962) the effects of co-chloroacetophenone (CAP), which is an irreversible —SH inhibitor, on the morphogenesis of chick embryos cultured in vitro were reported. Brachet (1950) suggested that the —SH-containing proteins might be active in induction. Rapkine & Brachet (1951) studied the effect of monoiodoacetate on the amphibian organizer and observed t...
Rhagomys rufescens (Rodentia: Sigmodontinae) is an endemic species of the Atlantic forest from Southern and Southeastern Brazil. Some authors consider Rhagomys as part of the tribe Thomasomyini; but its phylogenetic relationships remain unclear. Chromosomal studies on eight specimens of Rhagomys rufescens revealed a diploid number of 2n = 36 and a number of autosome arms FN = 50. GTG, CBG and A...
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