نتایج جستجو برای: استئاتوهپاتیت غیرالکلی nash
تعداد نتایج: 14610 فیلتر نتایج به سال:
The aim of this study was to clarify the significance of DNA methylation alterations during non-alcoholic steatohepatitis (NASH)-related hepatocarcinogenesis. Single-CpG-resolution genome-wide DNA methylation analysis was performed on 264 liver tissue samples using the Illumina Infinium HumanMethylation450 BeadChip. After Bonferroni correction, 3331 probes showed significant DNA methylation alt...
Every real algebraic variety is isomorphic to the set of totally mixed Nash equilibria of some three-person game, and also to the set of totally mixed Nash equilibria of an N-person game in which each player has two pure strategies. From the Nash-Tognoli Theorem it follows that every compact differentiable manifold can be encoded as the set of totally mixed Nash equilibria of some game. Moreove...
Lack of exercise and excessive food intake are known to be the important causes of nonalcoholic steatohepatitis (NASH). To elucidate the relationship between lifestyle and NASH, we surveyed exercise and dietary habits, comparing them among 171 biopsy-proven NASH patients, 29 nonalcoholic fatty liver (NAFL) patients and 49 normal subjects. Dietary habits including the duration of dinner time, am...
Non-alcoholic steatohepatitis (NASH) is a liver disease with the potential to lead to cirrhosis and hepatocellular carcinoma. Interleukin-6 (IL-6) has been implicated in the pathogenesis of NASH, with the so-called IL-6 'trans-signaling' cascade being responsible for the pro-inflammatory actions of this cytokine. We aimed to block IL-6 'trans-signaling', using a transgenic mouse that overexpres...
Nonalcoholic fatty liver disease (NAFLD) has increased in parallel with central obesity, and its prevalence is anticipated to increase as the obesity epidemic remains unabated. NAFLD is now the most common cause of chronic liver disease in developed countries and is defined as excessive lipid accumulation in the liver, that is, hepatosteatosis. NAFLD ranges in severity from benign fatty liver t...
زمینه و هدف: بیماری کبد چرب غیرالکلی (nafld) شایع ترین نوع بیماری کبدی است. چاقی یک عامل پیشگویی کننده برای خطر ابتلا به این بیماری در جوامع عمومی محسوب می شود. هدف از این مطالعه بررسی شاخص های تن سنجی در افراد مبتلا به کبد چرب غیرالکلی و مقایسه آن با گروه سالم می باشد. مواد و روش ها: این مطالعه از نوع مورد-شاهدی بوده که بر روی 94 فرد بیمار مبتلا به nafld (کبد چرب) و 100 فرد سالم انجام شد. قد،...
هدف: هدف از این تحقیق تعیین تأثیر 12 هفته تمرین اینتروال شدید بر سطوح پلاسمایی لپتین، آدیپونکتین و شاخص مقاومتبهانسولین مردان چاق مبتلا به کبد چرب با محدوده سنی 20 تا 35 سال بود. روش شناسی: آزمودنیهای این تحقیق، شامل 38 مرد چاق مبتلا به کبد چرب غیرالکلی با میانگین سن 2/6±5/28 سال، وزن 8/11±4/95 کیلوگرم و قد 7/14±6/178 سانتیمتر بودند که به طور تصادفی به دو گروه تجربی (18=n) و کنترل (20=n) ت...
OBJECTIVES Non-alcoholic steatohepatitis (NASH), is an important component of Non-alcoholic fatty liver disease (NAFLD) spectrum, which progresses to the end stage liver disease, if not diagnosed and treated properly. The disproportionate production of pro- and anti-inflammatory adipokines secreted from fat contributes to the pathogenesis of NASH. In this study, the comparative effect of piogli...
The notion of Nash equilibria plays a key role in the analysis of strategic interactions in the framework of N player games. Analysis of Nash equilibria is however a complex issue when the number of players is large. In this article, we emphasize the role of optimal transport theory in (i) the passage from Nash to Cournot-Nash equilibria as the number of players tends to infinity and (ii) the a...
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