BACKGROUND Through their increased potential to be engaged and processed by dendritic cells (DCs), nanovaccines consisting of Poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with both antigenic moieties and adjuvants are attractive candidates for triggering specific defense mechanisms against intracellular pathogens. The aim of the present study was to evaluate the immunogen...

Through the use of site-directed mutagenesis and chemical rescue, we have identified the proton acceptor for redox-active tyrosine D in photosystem II (PSII). Effects of chemical rescue on the tyrosyl radical were monitored by EPR spectroscopy. We also have acquired the Fourier-transform infrared (FT-IR) spectrum associated with the oxidation of tyrosine D and concomitant protonation of the acc...

Racemic 2'-deoxy-3'-thiacytidine (BCH 189) is a dideoxycytidine analog having a sulfur atom in place of the 3' carbon. The enantiomers of BCH 189 have been resolved and found to be equipotent in antiviral activity against human immunodeficiency virus types 1 and 2. However, the (-)-enantiomer (3TC) is considerably less cytotoxic than the (+)-enantiomer.

AMA Podolecki T, Streb W, Głowacki J, Kalarus Z. Late presentation of the Bland-White-Garland syndrome. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2023;19(2):188-189. doi:10.5114/aic.2023.129219. APA Podolecki, T., Streb, W., Głowacki, J., & Kalarus, (2023). Interwencyjnej, 19(2), 188-189. https://doi.org/10.5114/aic.2023.129219 Chicago Tomasz, Witold Jan and Zb...

Enhancing neurogenesis may be a powerful stroke therapy. Here, we tested in a rat model of ischemic stroke the beneficial effects of NSI-189, an orally active, new molecular entity (mol. wt. 366) with enhanced neurogenic activity, and indicated as an anti-depressant drug in a clinical trial (Fava et al., , Molecular Psychiatry, DOI: 10.1038/mp.2015.178) and being tested in a Phase 2 efficacy tr...

Combinatorics, Probability & Computing / Volume 11 / Issue 02 / March 2002, pp 179 189 DOI: 10.1017/S0963548301004928, Published online: 25 April 2002 Link to this article: http://journals.cambridge.org/abstract_S0963548301004928 How to cite this article: V. NIKIFOROV (2002). Some Inequalities for the Largest Eigenvalue of a Graph. Combinatorics, Probability & Computing, 11, pp 179-189 doi:10.1...