A multichannel terrain observation by progressive scans (TOPS) synthetic aperture radar (SAR) system is capable of imaging a wider swath with a higher azimuth resolution for improved moving target detection. For TOPS SAR, due to antenna beam steering, the azimuth bandwidth of background clutter is much larger than the instantaneous signal bandwidth. To overcome this problem, a method referred t...

Global production, consumption and emission of various chemicals continue to rise, despite growing evidence their harmful effects on environmental quality, food safety human health. Agronomy, a nature-dependent industry, is considered be extremely sensitive chemical pollution. Hence, it great importance for health study the migration biotransformation pollutants among agricultural elements, suc...

Products and processes innovation is a key-topic for the competitiveness of small and medium enterprises operating in the Information Technology field. The ESPINODE network links 18 European projects with the common goals of diffusing Software Process Improvement concepts and supporting the enterprises already involved in improvement experiments. This paper describes the methodology developed b...

A topological substructural molecular design approach (TOPS-MODE) has been used to formulate structural rules for binding of substrates of P-glycoprotein (P-gp). We first review some of the models developed in the recent literature for predicting binding to P-gp. Then, we develop a model using TOPS-MODE, which is able to identify 88.4% of substrates and 84.2% of non-substrates. When the model i...

We describe the design and implementation of a fast topology-based method for protein structure comparison. The approach uses the TOPS topological representation of protein structure, aligning two structures using a common discovered pattern and generating measure of distance derived from an insert score. Heavy use is made of a constraint-based pattern-matching algorithm for TOPS diagrams that ...

Candelas and Font introduced the notion of a ‘top’ as half of a three dimensional reflexive polytope and noticed that Dynkin diagrams of enhanced gauge groups in string theory can be read off from them. We classify all tops satisfying a generalized definition as a lattice polytope with one facet containing the origin and the other facets at distance one from the origin. These objects torically ...

Flowering tops of Ageratum conyzoides. Photo by Willcox.