نتایج جستجو برای: β lactams

تعداد نتایج: 181273  

2017
Hong-Ting Victor Lin Teresa Massam-Wu Chen-Ping Lin Yen-Jen Anna Wang Yu-Chi Shen Wen-Jung Lu Pang-Hung Hsu Yu-Hou Chen Maria Ines Borges-Walmsley Adrian Robert Walmsley

The genome sequence of V. cholerae O1 Biovar Eltor strain N16961 has revealed a putative antibiotic resistance (var) regulon that is predicted to encode a transcriptional activator (VarR), which is divergently transcribed relative to the putative resistance genes for both a metallo-β-lactamase (VarG) and an antibiotic efflux-pump (VarABCDEF). We sought to test whether these genes could confer a...

2015
Jia Yin Prabhakar M Shan Wang Shuo-Xi Liao Xin Peng Yan He Yi-Ran Chen Hua-Fang Shen Jin Su Ye Chen Yun-Xia Jiang Guo-Xia Zhang Hong-Wei Zhou

The adverse impact of antibiotics on the gut microbiota has attracted extensive interest, particularly due to the development of microbiome research techniques in recent years. However, a direct comparison of the dynamic effects of various types of antibiotics using the same animal model has not been available. In the present study, we selected six antibiotics from four categories with the broa...

2017
Tasnim Hasan William Chik Sharon Chen Jen Kok

Introduction.Listeria monocytogenes is an uncommon cause of prosthetic valve endocarditis (PVE). Recommended antimicrobial therapy typically includes intravenous β-lactams with or without synergistic aminoglycosides. In vitro studies have previously identified antagonism when rifampicin has been used in combination with β-lactams. However, in vivo data of rifampicin use are limited despite its ...

2015
Hecheng Wang Haiwei Huang Jin Cao Dehua Chui Shengyuan Xiao

High performance liquid chromatography tandem mass spectrometry (HPLC MS) has been widely used for β-lactam antibiotics determination. However, its application to identify impurities of these frequently used drugs is not sufficient at present. In this job, characteristic profiles of the collision induced dissociation (CID) spectra of both β-lactams and ring-opened β-lactams were extracted from ...

Journal: :Antimicrobial agents and chemotherapy 2013
Lindsey P Koliscak James W Johnson James R Beardsley David P Miller John C Williamson Vera P Luther Christopher A Ohl

Antibiotic selection is challenging in patients with severe β-lactam allergy due to declining reliability of alternate antibiotics. Organisms isolated from these patients may exhibit unique resistance phenotypes. The objective of this study was to determine which alternate antibiotics or combinations provide adequate empirical therapy for patients with β-lactam allergy who develop Gram-negative...

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