This paper reports a stimuli-responsive designer supramolecular polymer gel in dimethylsulphoxide (DMSO)/water (1:2) based on dipeptide amphiphile and β-cyclodextrin (β-CD) The contains caproic acid at the N terminus methyl ester C terminus. From X-ray single crystal diffraction, adopts kink-like conformation. self-assembled to form parallel sheet-like structure stabilized by multiple intermole...

Four new minor diterpene glycosides with a rare α-glucosyl linkage were isolated from a cyclodextrin glycosyltransferase glucosylated stevia extract containing more than 98% steviol glycosides. The new compounds were identified as 13-[(2-O-β-D-glucopyranosyl-3-O-(4-O-α-D-glucopyranosyl)-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid-[(4-O-α-D-glucopyranosyl-β-D-glucopyran...

Abstract: Introduction: The present study was carried out to formulate and evaluate orodispersible tablets of Apremilast with a purpose providing better patient compliance geriatric, pediatric, impaired, travelling non-cooperative patients suffering from psoriasis. Such are in need fast easy swallowing drug delivery system. Materials Methods: Apremilast-β-cyclodextrin inclusion complex prepared...

The aim of this study was to evaluate the antidegenerative effect in osteoarthritis damage of eriocitrin alone and eriocitrin formulated as innovative "dietary flavonoid supplement." A complexation between eriocitrin and hydroxypropyl β-cyclodextrin by solubilization/freeze-drying method was performed. The complex in solution was evaluated by phase solubility studies and the optimal 1 : 2 flava...

An inclusion complex consisting of a boronic acid fluorophore (C1-APB) and β-cyclodextrin (β-CyD) acts as a supramolecular sugar sensor whose response mechanism is based on photoinduced electron transfer (PET) from the excited pyrene to the boronic acid. We have investigated the PET process in C1-APB/CyD complexes by using time-resolved photoluminescence (TRPL) measurements at room temperature,...

The aim was to study the ability of bioadhesive cyclodextrin-poly(anhydride) nanoparticles as carriers for the oral delivery of atovaquone (ATO). In order to increase the loading capacity of ATO by poly(anhydride) nanoparticles, the following oligosaccharides were assayed: 2-hydroxypropyl-β-cyclodextrin (HPCD), 2,6-di-O-methyl-β-cyclodextrin (DCMD), randomly methylated-β-cyclodextrin (RMCD) and...

New drug delivery systems for wound healing applications based on α/β/γ-cyclodextrin (α/β/γ-CD) acrylic (A) and styrenic (S) monomers have been synthesized co-polymerized with 2-hydroxyethyl methacrylate (HEMA) via a cryo-polymerization technique.

Climate models show that particles formed by nucleation can affect cloud cover and, therefore, the earth's radiation budget. Measurements worldwide show that nucleation rates in the atmospheric boundary layer are positively correlated with concentrations of sulfuric acid vapor. However, current nucleation theories do not correctly predict either the observed nucleation rates or their functional...

In order to find the most effective method to overcome seed dormancy in Teucrium chamaedrys  L. medicinal plant species the effect of some chemical and physical breaking methods including: cold stratification (5 °C), scarification with sandpaper, stratification with needle, concentrated sulfuric acid, gibberellic acid and combination of these methods were investigated. Treated seeds along with ...

in order to reduce the costs associated with poly-β-hydroxybutyrate production, growth and poly-β-hydroxybutyrate production of ralstonia eutropha were studied in batch culture on different carbon sources. experiments were designed and conducted to not only lower the cost of poly-β-hydroxybutyrate production by using inexpensive substrates, but also to increase poly-β-hydroxybutyrate production...