نتایج جستجو برای: β blockers

تعداد نتایج: 196219  

2015
Stacy Poe Robin H. Vandivier-Pletsch Michael Clay Hector R. Wong Erin Haynes Florence G. Rothenberg

BACKGROUND Elevated cardiac troponin (cTn) in the absence of acute coronary syndromes (ACS) is associated with increased mortality in critically ill patients. There are no evidence-based interventions that reduce mortality in this group. OBJECTIVES We performed a retrospective investigation of the Veterans Administration Inpatient Evaluation Center database to determine whether drugs used in ...

Journal: :Pediatrics 2016
Anthony J Mancini

Infantile hemangioma (IH) is the most common tumor of childhood, and although most lesions eventually involute, the proliferative phase may be associated with complications, such as ulceration, bleeding, functional compromise, and anatomic disfigurement. Rarely, IH can have major or life-threatening consequences, such as airway obstruction, high-output congestive heart failure, and consumptive ...

Journal: :Cardiology 2015
Edimar Alcides Bocchi Michael Böhm Jeffrey S Borer Ian Ford Michel Komajda Karl Swedberg Luigi Tavazzi

OBJECTIVES We explored the prescription of β-blockers with ivabradine in patients with systolic heart failure, focusing on the most frequently coprescribed β-blocker, carvedilol. METHODS We analyzed outcomes in SHIFT patients with systolic heart failure who were prescribed β-blockers (carvedilol, bisoprolol, metoprolol, or nebivolol) with ivabradine or placebo. Analysis was by intention to tr...

Journal: :Medicine 2016
Vincent Yi-Fong Su Yu-Sheng Chang Yu-Wen Hu Man-Hsin Hung Shuo-Ming Ou Fa-Yauh Lee Kun-Ta Chou Kuang-Yao Yang Diahn-Warng Perng Tzeng-Ji Chen Chia-Jen Liu

Beta (β)-blockers are under-prescribed in patients with heart failure (HF) and concurrent chronic obstructive pulmonary disease (COPD) due to concerns about adverse pulmonary effects and a poor understanding of the effects of these drugs. We aimed to evaluate the survival effects of β-blockers in patients with coexistent HF and COPD. Using the Taiwan National Health Insurance Research Database,...

2015
David A Springate Darren M Ashcroft Evangelos Kontopantelis Tim Doran Ronan Ryan David Reeves

OBJECTIVES To conduct a fully independent, external validation of a research study based on one electronic health record database using a different database sampling from the same population. DESIGN Retrospective cohort analysis of β-blocker therapy and all-cause mortality in patients with cancer. SETTING Two UK national primary care databases (PCDs): the Clinical Practice Research Datalink...

Journal: :European heart journal. Cardiovascular pharmacotherapy 2015
Jonathan De Blois Morten Wang Fagerland Morten Grundtvig Anne Grete Semb Lars Gullestad Arne Westheim Torstein Hole Dan Atar Stefan Agewall

AIMS To assess the adherence to heart failure (HF) guidelines for angiotensin-converting enzyme-I (ACE-I), angiotensin II receptor blockers (ARB), and β-blockers and the possible association of ACE-I or ARB, β-blockers, and statins with survival in the large contemporary Norwegian Heart Failure Registry. METHODS AND RESULTS The study included 5761 outpatients who were diagnosed with HF of any...

Journal: :Hypertension 2016
Giacomo Pucci Maria Giovanna Ranalli Francesca Battista Giuseppe Schillaci

β-Blockers are less effective than other antihypertensive drug classes in reducing central systolic blood pressure (cSBP) as compared with peripheral SBP (pSBP). Whether this effect is less pronounced with vasodilating β-blockers (VBB) when compared with nonvasodilating β-blockers (NVBB) remains unsettled. We conducted a systematic review and meta-analysis of randomized trials exploring the eff...

2017
Min Jin Lee Sang Soo Kim In Joo Kim Sang Heon Song Eun Heui Kim Ji Yeong Seo Jong Ho Kim Sungsu Kim Yun Kyung Jeon Bo Hyun Kim Yong Ki Kim

Urinary angiotensinogen (AGT) is potentially a specific biomarker for the status of the intrarenal renin-angiotensin system (RAS) in patients with diabetes mellitus. We explored whether changes in urinary AGT excretion levels were associated with the deterioration of kidney function in type 2 diabetes patients with preserved kidney function. Urinary baseline AGT levels were measured in 118 type...

Journal: :BMJ 2016
Dipak Kotecha Luis Manzano Henry Krum Giuseppe Rosano Jane Holmes Douglas G Altman Peter D Collins Milton Packer John Wikstrand Andrew J S Coats John G F Cleland Paulus Kirchhof Thomas G von Lueder Alan S Rigby Bert Andersson Gregory Y H Lip Dirk J van Veldhuisen Marcelo C Shibata Hans Wedel Michael Böhm Marcus D Flather

OBJECTIVES To determine the efficacy and tolerability of β blockers in a broad age range of women and men with heart failure with reduced ejection fraction (HFrEF) by pooling individual patient data from placebo controlled randomised trials. DESIGN Prospectively designed meta-analysis of individual patient data from patients aged 40-85 in sinus rhythm at baseline, with left ventricular ejecti...

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