Despite lots of research on the pathogenesis of acne, the development of new therapeutic agents is still stagnant. Conventional agents which target multiple pathological processes have some serious side effects and this makes seeking new treatment options important for treating acne. As new therapeutic options, researchers are focusing on natural products, synthetic drugs and devices. From natu...

The world is endangered by the COVID‐19 pandemic caused SARS‐CoV‐2, people are dying in thousands every day, and without an actual treatment, it seems that bringing this global health problem to a quit impossible. Natural products have been constant use since ancient times proven time be effective. Medicinal plants from Indonesia may lead discovery of novel drugs. Mangosteen or Garcinia mangost...

The mangosteen (Garcinia mangostana) is a tropical fruit native to Southeast Asia and has long been reported to contain multiple health promoting properties. This fruit is an abundant source of xanthones, a class of polyphenolic compounds with a distinctive tricyclic aromatic ring system and is largely responsible for its biological activities including anti-cancer activity. Herein we describe ...

The goal of this work was to optimize the combination natural dyes producing panchromatic absorption matched AM1.5 solar spectrum for use in dye sensitized cells (DSSCs). Six classes (Anthocyanins, Betalins, Chlorophyll, Xanthonoids, Curcuminoids and Phycobilins) were explored. UV-Vis data radial basis function interpolation used model absorbance 2568 combinations, three objective functions det...

As part of ongoing research on cancer chemopreventive agents from botanical dietary supplements, Garcinia mangostana L. (commonly known as mangosteen) was selected for detailed study. Repeated chromatography of a CH2Cl2-soluble extract of the pericarp led to the isolation of two new highly oxygenated prenylated xanthones, 8-hydroxycudraxanthone G (1) and mangostingone [7-methoxy-2-(3-methyl-2-b...