Vol. 28, No. 3, 2016 393 Received March 16, 2015, Revised May 4, 2015, Accepted for publication June 1, 2015 Corresponding author: Jae Eun Choi, Department of Dermatology, Anam Hospital, Korea University College of Medicine, 73 Inchon-ro, Seongbukgu, Seoul 02841, Korea. Tel: 82-2-920-5470, Fax: 82-2-928-7540, E-mail: [email protected] This is an Open Access article distributed under the terms of...

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OBJECTIVES To evaluate and describe the anti-herpesvirus effect of ASP2151, amenamevir, a novel non-nucleoside oxadiazolylphenyl-containing herpesvirus helicase-primase complex inhibitor. METHODS The inhibitory effect of ASP2151 on enzymatic activities associated with a recombinant HSV-1 helicase-primase complex was assessed. To investigate the effect on viral DNA replication, we analysed vir...

childhood. Ambulatory Child Health. 2000;6:59-66. 4. Kalman CM, Laskin OL. Herpes zoster and zosteriform herpes simplex virus infections in immunocompetent adults. Am J Medic. 1986;81:775-8. 5. Nikkels AF, Nikkels-Tassoudji N, Piérard GE. Revisiting childhood herpes zoster. pediatr dermatol. 2004; 21:18-23. 6. Kakourou T, Theodoridou M, Mostrou G, Syriopoulou V, Papadogeorgaki H, Constantopoulu...

When herpes simplex virus was inoculated into the flank of a BALB/c mouse by scarification, the local replication of virus was followed by the establishment of an acute ganglionic infection. The subsequent centrifugal spread of this virus along nerves to the skin of the whole dermatome led to the development of a bandlike "zosteriform" rash. This represents a highly reproducible system in which...

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