BACKGROUND Mucopolysaccharidosis type IIID (MPS-IIID), or Sanfilippo syndrome type D, is a rare autosomal recessive lysosomal storage disorder caused by mutations in the N-acetylglucosamine-6-sulfatase (GNS) gene, leading to impaired degradation of heparan sulfate. OBJECTIVES To report the natural history of MPS-IIID in 2 siblings described by Kaplan and Wolfe in 1987 and to study the phenoty...

This study was carried out at Federal Polytechnic; Ado Ekiti in state on geochemical appraisal of three different genetically derived lateritic soils from south western Nigeria and their respective engineering performance 2019. Twelve (12) disturbed soil samples were collected granite (GDS), gneiss (GNS) migmatite (MGS) rock terrains. These four horizons 0.5m intervals, resulting into a maximum...

to study the tolerance of genotypes under terminal drought stress, 20 promising winter and facultative bread wheat genotypes were evaluated at karadj, ardebil, arak and hamedan agricultural research stations during 2001-02 cropping season. the experimental design in all the locations was randomized complete block of three replications. grain yield (yld), harvest index (hi), grain number per spi...

INTRODUCTION A 13-year-old child was clinically diagnosed with mucopolysaccharidosis type VI-Maroteaux-Lamy syndrome (MPS VI) at the age of 5 years, and the diagnosis was confirmed biochemically and genetically (homozygous mutation in ARSB gene). At that time, his older brother manifested with increasing severe mental retardation. His urinary glycosaminoglycan excretion in urine was elevated, b...

The resonant transmission of self-collimated beams through zigzag-box resonators is demonstrated experimentally and numerically. Numerical simulations show that the flat-wavefront and the width of the beam are well maintained after passing through zigzag-box resonators because the up and the down zigzag-sides prevent the beam from spreading out and the wavefront is perfectly reconstructed by th...

Abstract We prove that the generator of $$L^2$$ L 2 implementation a KMS-symmetric quantum Markov semigroup can be expressed as square derivation with values in Hilbert bimodule, extending earlier results by Cipriani and Sauvageot for tracially symmetric semigroups seco...

Thepurpose of this studywas todetermine the capacity ofMK-1775, apotentWee-1 inhibitor, to abrogate the radiation-induced G2 checkpoint arrest andmodulate radiosensitivity in glioblastoma cell models and normal human astrocytes. The radiation-induced checkpoint response of established glioblastoma cell lines, glioblastoma neural stem (GNS) cells, and astrocytes were determined in vitro by flow ...

BACKGROUND In sentinel node (SN) detection for cases of early gastric cancer, the submucosal dye injection method appears to be more reasonable than the subserosal injection. To compare the two injection methods, we have focused on the rate of concordance between hot nodes (HNs) obtained from the radioisotope (RI) method and green nodes (GNs) obtained from the dye-guided method in addition to t...

In this paper, preparation, characterization and application of a new sensor for fast and simple determination of trace amount of diazepam were described. This sensor is based on Ag nanodendrimers (AgNDs) supported by graphene nanosheets modified glassy carbon electrode (GNs/GCE). The AgNDs were directly electrodeposited on the surface of electrode via potentiostatic method without using any te...