The postsegregational killing system of pSM19035 plasmid consists of the proteins Zeta and Epsilon, a toxin and an antidote, respectively. Zeta mutants were isolated with the use of Bacillus subtilis strain with the zeta gene under control of an inducible promoter integrated into the chromosome. Results of mutant analysis point to the amino terminal part of the Zeta protein as being responsible...

Complete zeta-function approach to the electromagnetic Casimir effect for spheres and circles. Abstract A technique for evaluating the electromagnetic Casimir energy in situations involving spherical or circular boundaries is presented. Zeta function regularization is unambiguously used from the start and the properties of Bessel and related zeta functions are central. Nontrivial results concer...

We present a unified approach which gives completely elementary proofs of three weighted sum formulae for double zeta values. This approach also leads to new evaluations of sums relating to the harmonic numbers, the alternating double zeta values, and the Witten zeta function. We discuss a heuristic for finding or dismissing the existence of similar simple sums. We also produce some new sums fr...

This paper is a study of summability methods that are based on the Riemann Zeta function. A limitation theorem is proved which gives a necessary condition for a sequence x to be zeta summable. A zeta summability matrix Z associated with a real sequence is introduced; a necessary and sufficient condition on the sequence such that Z maps 11 to 11 is established. Results comparing the strength of ...

Most genomes of bacteria contain toxin-antitoxin (TA) systems. These gene systems encode a toxic protein and its cognate antitoxin. Upon antitoxin degradation, the toxin induces cell stasis or death. TA systems have been linked with numerous functions, including growth modulation, genome maintenance, and stress response. Members of the epsilon/zeta TA family are found throughout the genomes of ...

Phosphatidic acid (PA) is produced rapidly in agonist-stimulated cells, but the physiological function of this PA is unknown. We have examined the effects of PA on distinct isoforms of protein kinase C (PKC) using a new cell-free assay system. Addition of PA to cytosol from COS cells overexpressing PKC-alpha, -epsilon or -zeta differentially-activated all three isotypes, as shown by PKC autopho...

14-3-3 proteins may function as adapter or scaffold proteins in signal transduction pathways. We reported previously that several 14-3-3 isotypes bind to protein kinase C (PKC)-zeta and facilitate coupling of PKC-zeta to Raf-1 [van der Hoeven, van der Wal, Ruurs, van Dijk and van Blitterswijk (2000) Biochem. J. 345, 297-306], an event that boosts the mitogen-activated protein kinase (ERK) pathw...

Differential Expression of TcR-CD3 Zeta as Evidence for Altered Immunoregulation in Preeclamptic vs. Normotensive Women Garrett K. Lam, MD, Paul W. Whitecar, MD, Susan Orton, PhD, Kim A. Boggess, MD, Douglas D. Taylor, PhD Objective: To exhibit and quantify the difference in modulation of CD3-zeta protein (an integral component of the T-cell receptor) in preeclamptic and normotensive women. Stu...

In this paper, we initiate a geometrically oriented study of local and global non-abelian zeta functions for curves. This consists of two parts: construction and justification. For the construction, we first use moduli spaces of semi-stable bundles to introduce a new type of zeta functions for curves defined over finite fields. Then, we prove that these new zeta functions are indeed rational an...

Using monolayers of human intestinal (Caco-2) cells, we showed that epidermal growth factor (EGF) protects intestinal barrier integrity against oxidant injury by protecting the microtubules and that protein kinase C (PKC) is required. Because atypical PKC-zeta isoform is abundant in wild-type (WT) Caco-2 cells, we hypothesized that PKC-zeta mediates, at least in part, EGF protection. Intestinal...