Suggested scheme for the treatment of onychomycosis A stepped therapeutic approach to the treatment of onychomycosis is suggested. The risks of failure of treatment include the fungal involvement of the lunula portion, the lateral edge of the nail and the subungual area. Infection of the subungual area may lead to extensive onycholysis or dermatophytoma presenting as a hard subungual mass or as...

The yellow nail syndrome (YNS) is a rare clinical entity characterised by slow growing yellow discoloured nails in association with peripheral lymphoedema, pulmonary manifestation (bronchiectasis, pleural effusions), and chronic sinusitis. 1 About 100 cases of YNS have been described in the literature but it has never been associated with ocular manifestations. 2 We report one patient with YNS ...

A54-year-old woman was referred for evaluation of possible cor pulmonale based on the presence of dyspnea, chronic productive cough, and bilateral leg edema for 8 years. For about 8 years, her nails had been thick, brown-yellowish and would break easily. The nail grew very slowly and sometimes separated from its bed. The appearance of the nails did not change after 7 courses of antimycotic ther...

We believe that dynamic parameters such as stroke volume variation are currently the best markers of volume responsiveness.1 While the models of Guyton and Starling are magnificent in their simplicity, therapeutic interventions based on these principles may lead to therapeutic errors in complex critically ill patients. This is demonstrated by the fact that no clinical study (of which we are awa...

Yellow nail syndrome (YNS) can be associated with a pleural effusion (PE) but the characteristics of these patients are not well defined. We performed a systematic review across four electronic databases for studies reporting clinical findings, PE characteristics, and most effective treatment of YNS. Case descriptions and retrospective studies were included, unrestricted by year of publication....

INTRODUCTION Nephrotic syndrome is considered a rare cause of chylous ascites. Intestinal lymphangiectasia in a background of chylous ascites and without any lymphatic obstruction has been reported in association with yellow nail syndrome, which is a rare clinical occurrence in itself. The existence of chylous ascites, duodenal and splenic lymphangiectasia (without any lymphatic obstruction) an...

COMMUNICATIONS TO THE EDITOR 243 O’Donohue the pleural manifestation occurred by accident, not associated with the common etiologic relationship of the yellow nail syndrome, namely, the primarily defective lymphatic circulation. The history data on their patient as having profound mental retardation and being under continuous use of anticonvulsants and sedatives, suggests a propensity toward th...